Deuxième partie : Les récepteurs de la neurotensine :

V - Références Bibliographiques :

Ahmad, S., Berezin, I., Vincent, J.P. and Daniel, E.E. 1987 Neurotensin receptors in canine intestinal smooth muscle : preparation of plasma membranes and characterization of (Tyr³-¹²⁵I)-labelled neurotensin binding. Biochim Biophys Acta, 896, 224-238.

Ahmad, S. and Daniel, E.E. 1991 Receptors for neurotensin in canine small intestine. Peptides, 12, 623-629.

al-Rodhan, N.R., Richelson, E., Gilbert, J.A., McCormick, D.J., Kanba, K.S., Pfenning, M.A., Nelson, A., Larson, E.W. and Yaksh, T.L. 1991 Structure-antinociceptive activity of neurotensin and some novel analogues in the periaqueductal gray region of the brainstem. Brain Res, 557, 227-235.

Alexander, M.J. and Leeman, S.E. 1998 Widespread expression in adult rat forebrain of mRNA encoding high-affinity neurotensin receptor. J Comp Neurol, 402, 475-500.

Amar, S., Kitabgi, P. and Vincent, J.P. 1986 Activation of phosphatidylinositol turnover by neurotensin receptors in the human colonic adenocarcinoma cell line HT29. FEBS Lett, 201, 31-36.

Amar, S., Kitabgi, P. and Vincent, J.P. 1987 Stimulation of inositol phosphate production by neurotensin in neuroblastoma N1E115 cells: implication of GTP-binding proteins and relationship with the cyclic GMP response. J Neurochem, 49, 999-1006.

Amar, S., Mazella, J., Checler, F., Kitabgi, P. and Vincent, J.P. 1985 Regulation of cyclic GMP levels by neurotensin in neuroblastoma clone N1E115. Biochem Biophys Res Commun, 129, 117-125.

Azzi, M., Boudin, H., Mahmudi, N., Pelaprat, D., Rostene, W. and Berod, A. 1996 In vivo regulation of neurotensin receptors following long-term pharmacological blockade with a specific receptor antagonist. Brain Res Mol Brain Res, 42, 213-221.

Battey, F.D., Gafvels, M.E., FitzGerald, D.J., Argraves, W.S., Chappell, D.A., Strauss, J.F., 3rd and Strickland, D.K. 1994 The 39-kDa receptor-associated protein regulates ligand binding by the very low density lipoprotein receptor. J Biol Chem, 269, 23268-23273.

Bauer, B., Ehinger, B., Tornqvist, K. and Waga, J. 1985 Neurotransmitter release by certain neuropeptides in the chicken retina. Acta Ophthalmol (Copenh), 63, 581-587.

Bolden-Watson, C., Watson, M.A., Murray, K.D., Isackson, P.J. and Richelson, E. 1993 Haloperidol but not clozapine increases neurotensin receptor mRNA levels in rat substantia nigra. J Neurochem, 61, 1141-1143.

Borges, S., Gleason, E., Frerking, M. and Wilson, M. 1996 Neurotensin induces calcium oscillations in cultured amacrine cells. Vis Neurosci, 13, 311-318.

Botto, J.M., Chabry, J., Nouel, D., Paquet, M., Seguela, P., Vincent, J.P., Beaudet, A. and Mazella, J. 1997a Identification in the rat neurotensin receptor of amino-acid residues critical for the binding of neurotensin. Brain Res Mol Brain Res, 46, 311-317.

Botto, J.M., Chabry, J., Sarret, P., Vincent, J.P. and Mazella, J. 1998 Stable expression of the mouse levocabastine-sensitive neurotensin receptor in HEK 293 cell line: binding properties, photoaffinity labeling, and internalization mechanism. Biochem Biophys Res Commun, 243, 585-590.

Botto, J.M., Guillemare, E., Vincent, J.P. and Mazella, J. 1997b Effects of SR 48692 on neurotensin-induced calcium-activated chloride currents in the Xenopus oocyte expression system: agonist-like activity on the levocabastine-sensitive neurotensin receptor and absence of antagonist effect on the levocabastine insensitive neurotensin receptor. Neurosci Lett, 223, 193-196.

Botto, J.M., Sarret, P., Vincent, J.P. and Mazella, J. 1997c Identification and expression of a variant isoform of the levocabastine-sensitive neurotensin receptor in the mouse central nervous system. FEBS Lett, 400, 211-214.

Botto, J.M., Vincent, J.P. and Mazella, J. 1997d Existence of two translation initiation sites leading to the expression of two proteins from the rat high-affinity neurotensin-receptor cDNA: possible regulation by the 5' end non-coding region. Biochem J, 324, 389-393.

Boudin, H., Grauz-Guyon, A., Faure, M.P., Forgez, P., Lhiaubet, A.M., Dennis, M., Beaudet, A., Rostene, W. and Pelaprat, D. 1995 Immunological recognition of different forms of the neurotensin receptor in transfected cells and rat brain. Biochem J, 305, 277-283.

Boudin, H., Lazaroff, B., Bachelet, C.M., Pelaprat, D., Rostene, W. and Beaudet, A. 2000 Immunologic differentiation of two high-affinity neurotensin receptor isoforms in the developing rat brain. J Comp Neurol, 425, 45-57.

Boudin, H., Pelaprat, D., Rostene, W. and Beaudet, A. 1996 Cellular distribution of neurotensin receptors in rat brain: immunohistochemical study using an antipeptide antibody against the cloned high affinity receptor. J Comp Neurol, 373, 76-89.

Bozou, J.C., Amar, S., Vincent, J.P. and Kitabgi, P. 1986 Neurotensin-mediated inhibition of cyclic AMP formation in neuroblastoma N1E115 cells: involvement of the inhibitory GTP-binding component of adenylate cyclase. Mol Pharmacol, 29, 489-496.

Bozou, J.C., de Nadai, F., Vincent, J.P. and Kitabgi, P. 1989a Neurotensin, bradykinin and somatostatin inhibit cAMP production in neuroblastoma N1E115 cells via both pertussis toxin sensitive and insensitive mechanisms. Biochem Biophys Res Commun, 161, 1144-1150.

Bozou, J.C., Rochet, N., Magnaldo, I., Vincent, J.P. and Kitabgi, P. 1989b Neurotensin stimulates inositol trisphosphate-mediated calcium mobilization but not protein kinase C activation in HT29 cells. Involvement of a G-protein. Biochem J, 264, 871-878.

Buck, S.H., Deshmukh, P.P., Burks, T.F. and Yamamura, H.I. 1981 A survey of substance P, somatostatin, and neurotensin levels in aging in the rat and human central nervous system. Neurobiol Aging, 2, 257-264.

Cadet, J.L., Kujirai, K., Carlson, E. and Epstein, C.J. 1993 Autoradiographic distribution of [3H]neurotensin receptors in the brains of superoxide dismutase transgenic mice. Synapse, 14, 24-33.

Canonico, P.L., Sortino, M.A., Speciale, C. and Scapagnini, U. 1985a Neurotensin stimulates polyphosphoinositide breakdown and prolactin release in anterior pituitary cells in culture. Mol Cell Endocrinol, 42, 215-220.

Canonico, P.L., Speciale, C., Sortino, M.A. and Scapagnini, U. 1985b Involvement of arachidonate metabolism in neurotensin-induced prolactin release in vitro. Am J Physiol, 249, E257-263.

Carraway, R. and Leeman, S.E. 1973 The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J Biol Chem, 248, 6854-6861.

Carraway, R.E., Demers, L.M. and Leeman, S.E. 1976 Hyperglycemic effect of neurotensin, a hypothalamic peptide. Endocrinology, 99, 1452-1462.

Castel, M.N., Faucher, D., Cuine, F., Dubedat, P., Boireau, A. and Laduron, P.M. 1991 Identification of intact neurotensin in the substantia nigra after its retrograde axonal transport in dopaminergic neurons. J Neurochem, 56, 1816-1818.

Castel, M.N., Malgouris, C., Blanchard, J.C. and Laduron, P.M. 1990 Retrograde axonal transport of neurotensin in the dopaminergic nigrostriatal pathway in the rat. Neuroscience, 36, 425-430.

Castel, M.N., Woulfe, J., Wang, X., Laduron, P.M. and Beaudet, A. 1992 Light and electron microscopic localization of retrogradely transported neurotensin in rat nigrostriatal dopaminergic neurons. Neuroscience, 50, 269-282.

Chabry, J., Botto, J.M., Nouel, D., Beaudet, A., Vincent, J.P. and Mazella, J. 1995 Thr-422 and Tyr-424 residues in the carboxyl terminus are critical for the internalization of the rat neurotensin receptor. J Biol Chem, 270, 2439-2442.

Chabry, J., Gaudriault, G., Vincent, J.P. and Mazella, J. 1993 Implication of various forms of neurotensin receptors in the mechanism of internalization of neurotensin in cerebral neurons. J Biol Chem, 268, 17138-17144.

Chabry, J., Labbe-Jullie, C., Gully, D., Kitabgi, P., Vincent, J.P. and Mazella, J. 1994 Stable expression of the cloned rat brain neurotensin receptor into fibroblasts: binding properties, photoaffinity labeling, transduction mechanisms, and internalization. J Neurochem, 63, 19-27.

Chalon, P., Vita, N., Kaghad, M., Guillemot, M., Bonnin, J., Delpech, B., Le Fur, G., Ferrara, P. and Caput, D. 1996 Molecular cloning of a levocabastine-sensitive neurotensin binding site. FEBS Lett, 386, 91-94.

Checler, F., Dauch, P., Masuo, Y. and Vincent, J.P. 1991 Neurotensin and neuromedin N are differently metabolized in ventral tegmental area and nucleus accumbens. J Neurochem, 56, 1320-1328.

Checler, F., Mazella, J., Kitabgi, P. and Vincent, J.P. 1986a High-affinity receptor sites and rapid proteolytic inactivation of neurotensin in primary cultured neurons. J Neurochem, 47, 1742-1748.

Checler, F., Vincent, J.P. and Kitabgi, P. 1986b Neuromedin N: high affinity interaction with brain neurotensin receptors and rapid inactivation by brain synaptic peptidases. Eur J Pharmacol, 126, 239-244.

Coquerel, A., Dubuc, I., Kitabgi, P. and Costentin, J. 1988 Potentiation by thiorphan and bestatin of the naloxone-insensitive analgesic effects of neurotensin and neuromedin N. Neurochem. Int., 12, 361-366.

De Ceballos, M.L., Boyce, S., Taylor, M., Jenner, P. and Marsden, C.D. 1987 Age-related decreases in the concentration of Met- and Leu-enkephalin and neurotensin in the basal ganglia of rats. Neurosci Lett, 75, 113-117.

Dobie, D.J., Merchant, K.M., Hamblin, M.W., Vatassery, G.T., Dysken, M.W. and Dorsa, D.M. 1993 Blunting of the neurotensin mRNA response to haloperidol in the striatum of aging rats: possible relationship to decline in dopamine D2 receptor expression. Brain Res, 616, 105-113.

Donato di Paola, E., Cusack, B., Yamada, M. and Richelson, E. 1993 Desensitization and down-regulation of neurotensin receptors in murine neuroblastoma clone N1E-115 by [D-Lys8] neurotensin(8-13). J Pharmacol Exp Ther, 264, 1-5.

Dubuc, I., Costentin, J., Terranova, J.P., Barnouin, M.C., Soubrie, P., Le Fur, G., Rostene, W. and Kitabgi, P. 1994 The nonpeptide neurotensin antagonist, SR 48692, used as a tool to reveal putative neurotensin receptor subtypes. Br J Pharmacol, 112, 352-354.

Dubuc, I., Remande, S. and Costentin, J. 1999a The partial agonist properties of levocabastine in neurotensin-induced analgesia. Eur J Pharmacol, 381, 9-12.

Dubuc, I., Sarret, P., Labbe-Jullie, C., Botto, J.M., Honore, E., Bourdel, E., Martinez, J., Costentin, J., Vincent, J.P., Kitabgi, P. and Mazella, J. 1999b Identification of the receptor subtype involved in the analgesic effect of neurotensin. J Neurosci, 19, 503-510.

Duffty, P. and Bryan, M.H. 1982 Home apnea monitoring in "near-miss" sudden infant death syndrome and in sibblings of SIDS victims. Pediatrics, 70, 69-74.

Elde, R., Schalling, M., Ceccatelli, S., Nakanishi, S. and Hokfelt, T. 1990 Localization of neuropeptide receptor mRNA in rat brain: initial observations using probes for neurotensin and substance P receptors. Neurosci Lett, 120, 134-138.

Faull, R.L., Villiger, J.W. and Dragunow, M. 1989 Neurotensin receptors in the human spinal cord: a quantitative autoradiographic study. Neuroscience, 29, 603-613.

Faure, M.P., Alonso, A., Nouel, D., Gaudriault, G., Dennis, M., Vincent, J.P. and Beaudet, A. 1995a Somatodendritic internalization and perinuclear targeting of neurotensin in the mammalian brain. J Neurosci, 15, 4140-4147.

Faure, M.P., Labbe-Jullie, C., Cashman, N., Kitabgi, P. and Beaudet, A. 1995b Binding and internalization of neurotensin in hybrid cells derived from septal cholinergic neurons. Synapse, 20, 106-116.

Faure, M.P., Nouel, D. and Beaudet, A. 1995c Axonal and dendritic transport of internalized neurotensin in rat mesostriatal dopaminergic neurons. Neuroscience, 68, 519-529.

Feurle, G.E., Muller, B., Ohnheiser, G. and Baca, I. 1985 Action of neurotensin on size, composition, and growth of pancreas and stomach in the rat. Regul Pept, 13, 53-62.

Firth, S.I., Boelen, M.K. and Morgan, I.G. 1998 Enkephalin, neurotensin and somatostatin increase cAMP levels in the chicken retina. Aust N Z J Ophthalmol, 26 Suppl 1, S65-67.

Gailly, P., Najimi, M. and Hermans, E. 2000 Evidence for the dual coupling of the rat neurotensin receptor with pertussis toxin-sensitive and insensitive G-proteins [In Process Citation]. FEBS Lett, 483, 109-113.

Garver, D.L., Bissette, G., Yao, J.K. and Nemeroff, C.B. 1991 Relation of CSF neurotensin concentrations to symptoms and drug response of psychotic patients. Am J Psychiatry, 148, 484-488.

Gaudriault, G. and Vincent, J.P. 1992 Selective labeling of alpha- or epsilon-amino groups in peptides by the Bolton-Hunter reagent. Peptides, 13, 1187-1192.

Gaudriault, G., Zsurger, N. and Vincent, J.P. 1994 Compared binding properties of ¹²⁵I-labeled analogues of neurotensin and neuromedin N in rat and mouse brain. J Neurochem, 62, 361-368.

Gaudriault, G., Zsurger, N. and Vincent, J.P. 1996 Radiolabeled ligands specific for the G protein-coupled state of neurotensin receptors. J Neurochem, 67, 2590-2598.

Gilbert, J.A., Moses, C.J., Pfenning, M.A. and Richelson, E. 1986 Neurotensin and its analogs--correlation of specific binding with stimulation of cyclic GMP formation in neuroblastoma clone N1E-115. Biochem Pharmacol, 35, 391-397.

Gliemann, J., Nykjaer, A., Petersen, C.M., Jorgensen, K.E., Nielsen, M., Andreasen, P.A., Christensen, E.I., Lookene, A., Olivecrona, G. and Moestrup, S.K. 1994 The multiligand alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein (alpha 2MR/LRP). Binding and endocytosis of fluid phase and membrane-associated ligands. Ann N Y Acad Sci, 737, 20-38.

Goedert, M., Mantyh, P.W., Hunt, S.P. and Emson, P.C. 1984a Localization of specific neurotensin binding sites in the rat adrenal gland. Brain Res, 299, 389-392.

Goedert, M., Pittaway, K. and Emson, P.C. 1984b Neurotensin receptors in the rat striatum: lesion studies. Brain Res, 299, 164-168.

Govoni, S., Di Giovine, S., Battaini, F. and Trabucchi, M. 1986 Age-related changes in neurotensin content and receptors in various rat brain areas. Exp Aging Res, 12, 197-201.

Gully, D., Canton, M., Boigegrain, R., Jeanjean, F., Molimard, J.C., Poncelet, M., Gueudet, C., Heaulme, M., Leyris, R., Brouard, A. and et al. 1993 Biochemical and pharmacological profile of a potent and selective nonpeptide antagonist of the neurotensin receptor. Proc Natl Acad Sci U S A, 90, 65-69.

Hermans, E., Maloteaux, J.M. and Octave, J.N. 1992 Phospholipase C activation by neurotensin and neuromedin N in Chinese hamster ovary cells expressing the rat neurotensin receptor. Brain Res Mol Brain Res, 15, 332-338.

Hermans, E., Octave, J.N. and Maloteaux, J.M. 1994 Receptor mediated internalization of neurotensin in transfected Chinese hamster ovary cells. Biochem Pharmacol, 47, 89-91.

Hermans, E., Vanisberg, M.A., Geurts, M. and Maloteaux, J.M. 1997 Down-regulation of neurotensin receptors after ligand-induced internalization in rat primary cultured neurons. Neurochem Int, 31, 291-299.

Hermans-Borgmeyer, I., Hermey, G., Nykjaer, A. and Schaller, C. 1999 Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development. Brain Res Mol Brain Res, 65, 216-219.

Hermey, G., Riedel, I.B., Hampe, W., Schaller, H.C. and Hermans-Borgmeyer, I. 1999 Identification and characterization of SorCS, a third member of a novel receptor family. Biochem Biophys Res Commun, 266, 347-351.

Hernandez, D.E., Richardson, C.M., Nemeroff, C.B., Orlando, R.C., St-Pierre, S., Rioux, F. and Prange, A.J., Jr. 1984 Evidence for biological activity of two N-terminal fragments of neurotensin, neurotensin1-8 and neurotensin1-10. Brain Res, 301, 153-156.

Holst Pedersen, J., Skov Olsen, P. and Kirkegaard, P. 1986 Effect of neurotensin and neurotensin fragments on gastric acid secretion in man. Regul Pept, 15, 77-86.

Hosli, E., Stauffer, S. and Hosli, L. 1995 Autoradiographic and electrophysiological evidence for the existence of neurotensin receptors on cultured astrocytes. Neuroscience, 66, 627-633.

Jacobsen, L., Madsen, P., Moestrup, S.K., Lund, A.H., Tommerup, N., Nykjaer, A., Sottrup-Jensen, L., Gliemann, J. and Petersen, C.M. 1996 Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein. J Biol Chem, 271, 31379-31383.

James, D.E. and Piper, R.C. 1994 Insulin resistance, diabetes, and the insulin-regulated trafficking of GLUT-4. J Cell Biol, 126, 1123-1126.

Jolicoeur, F.B., Barbeau, A., Rioux, F., Quirion, R. and St-Pierre, S. 1981a Differential neurobehavioral effects of neurotensin and structural analogues. Peptides, 2, 171-175.

Jolicoeur, F.B., Rondeau, D., St-Pierre, S., Rioux, F. and Barbeau, A. 1981b Clinical pharmacology of apomorphine an other dopaminomimetics. In Gessa, J.L. and Corsini, G.U. (eds.), Clinical pharmacology of apomorphine an other dopaminomimetics. Raven Press, New York, pp. 19-25.

Kahn, A., Rebuffat, E., Blum, D., Sottiaux, M. and Muller, M.F. 1988 Aspects épidémiologiques du Syndrome de la mort subite du nourrisson. . Groupe d'étude de langue française de la mort subite et inexpliquée du nourrisson, pp. 1-31.

Kalivas, P.W., Richardson-Carlson, R. and Duffy, P. 1986 Neuromedin N mimics the actions of neurotensin in the ventral tegmental area but not in the nucleus accumbens. J Pharmacol Exp Ther, 238, 1126-1131.

Kanba, K.S., Kanba, S., Okazaki, H. and Richelson, E. 1986 Binding of [3H]neurotensin in human brain: properties and distribution. J Neurochem, 46, 946-952.

Kandror, K. and Pilch, P.F. 1994a Identification and isolation of glycoproteins that translocate to the cell surface from GLUT4-enriched vesicles in an insulin-dependent fashion. J Biol Chem, 269, 138-142.

Kandror, K.V. and Pilch, P.F. 1994b gp160, a tissue-specific marker for insulin-activated glucose transport. Proc Natl Acad Sci U S A, 91, 8017-8021.

Kandror, K.V. and Pilch, P.F. 1996 The insulin-like growth factor II/mannose 6-phosphate receptor utilizes the same membrane compartments as GLUT4 for insulin-dependent trafficking to and from the rat adipocyte cell surface. J Biol Chem, 271, 21703-21708.

Kandror, K.V., Yu, L. and Pilch, P.F. 1994 The major protein of GLUT4-containing vesicles, gp160, has aminopeptidase activity. J Biol Chem, 269, 30777-30780.

Keller, S.R., Scott, H.M., Mastick, C.C., Aebersold, R. and Lienhard, G.E. 1995 Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesicles [published erratum appears in J Biol Chem 1995 Dec 15;270(50):30236]. J Biol Chem, 270, 23612-23618.

Kenakin, T. 1995a Agonist-receptor efficacy II : agonist trafficking of receptor signals. TiPS, 16, 232-238.

Kenakin, T. 1995b Pharmalogical proteus. TiPS, 16, 256-258.

Kenakin, T. 1997 Agonist-specific receptor conformations. TiPS, 18, 416-417.

Kinney, C.H., Filiano, J. and Harper, M.R. 1992 The neuropathology of the sudden infant death syndrom. A review. J of Neuropath and Exp Neurol, 51, 115-126.

Kitabgi, P., Carraway, R., Van Rietschoten, J., Granier, C., Morgat, J.L., Menez, A., Leeman, S. and Freychet, P. 1977 Neurotensin: specific binding to synaptic membranes from rat brain. Proc Natl Acad Sci U S A, 74, 1846-1850.

Kitabgi, P. and Freychet, P. 1978 Effects of neurotensin on isolated intestinal smooth muscles. Eur J Pharmacol, 50, 349-357.

Kitabgi, P., Hamon, G. and Worcel, M. 1979 Electrophysiological study of the action of neurotensin on the smooth muscle of the guinea-pig taenia coli. Eur J Pharmacol, 56, 87-93.

Kitabgi, P., Kwan, C.Y., Fox, J.E. and Vincent, J.P. 1984 Characterization of neurotensin binding to rat gastric smooth muscle receptor sites. Peptides, 5, 917-923.

Kitabgi, P., Poustis, C., Granier, C., Van Rietschoten, J., Rivier, J., Morgat, J.L. and Freychet, P. 1980 Neurotensin binding to extraneural and neural receptors: comparison with biological activity and structure--activity relationships. Mol Pharmacol, 18, 11-19.

Kitabgi, P., Rostene, W., Dussaillant, M., Schotte, A., Laduron, P.M. and Vincent, J.P. 1987 Two populations of neurotensin binding sites in murine brain: discrimination by the antihistamine levocabastine reveals markedly different radioauto-graphic distribution. Eur J Pharmacol, 140, 285-293.

Kitabgi, P. and Vincent, J.P. 1981 Neurotensin is a potent inhibitor of guinea-pig colon contractile activity. Eur J Pharmacol, 74, 311-318.

H. Kiyama, S. Inagaki, S. Kito and M. Tohyama, 1987, Ontogeny of [3H]neurotensin binding sites in the rat cerebral cortex: autoradiographic study, Brain Res, 428, 2, 303-6.

Kopp, N., Deneroy, L., Saint-Pierre, G. and Jordan, D. 1992 Les anomalies du système nerveux dans le syndrome de mort subite du nourrisson. Pédiatrie, 47, 429-439.

Labbe-Jullie, C., Barroso, S., Nicolas-Eteve, D., Reversat, J.L., Botto, J.M., Mazella, J., Bernassau, J.M. and Kitabgi, P. 1998 Mutagenesis and modeling of the neurotensin receptor NTR1. Identification of residues that are critical for binding SR 48692, a nonpeptide neurotensin antagonist. J Biol Chem, 273, 16351-16357.

Labbe-Jullie, C., Botto, J.M., Mas, M.V., Chabry, J., Mazella, J., Vincent, J.P., Gully, D., Maffrand, J.P. and Kitabgi, P. 1995 [3H]SR 48692, the first nonpeptide neurotensin antagonist radioligand: characterization of binding properties and evidence for distinct agonist and antagonist binding domains on the rat neurotensin receptor. Mol Pharmacol, 47, 1050-1056.

Laget, P. 1973 Eléments de neuroanatomie fonctionnelle. Cervelet, mésencéphale et diencéphale.

Laurent, P., Clerc, P., Mattei, M.G., Forgez, P., Dumont, X., Ferrara, P., Caput, D. and Rostene, W. 1994 Chromosomal localization of mouse and human neurotensin receptor genes. Mamm Genome, 5, 303-306.

Le, F., Groshan, K., Zeng, X.P. and Richelson, E. 1997 Characterization of the genomic structure, promoter region, and a tetranucleotide repeat polymorphism of the human neurotensin receptor gene. J Biol Chem, 272, 1315-1322.

Lepee-Lorgeoux, I., Betancur, C., Rostene, W. and Pelaprat, D. 1999 Differential ontogenetic patterns of levocabastine-sensitive neurotensin NT2 receptors and of NT1 receptors in the rat brain revealed by in situ hybridization. Brain Res Dev Brain Res, 113, 115-131.

Lepee-Lorgeoux, I., Betancur, C., Souaze, F., Rostene, W., Berod, A. and Pelaprat, D. 2000 Regulation of the neurotensin NT(1) receptor in the developing rat brain following chronic treatment with the antagonist SR 48692. J Neurosci Res, 60, 362-369.

Lin, B.Z., Pilch, P.F. and Kandror, K.V. 1997 Sortilin is a major protein component of Glut4-containing vesicles. J Biol Chem, 272, 24145-24147.

Marcusson, E.G., Horazdovsky, B.F., Cereghino, J.L., Gharakhanian, E. and Emr, S.D. 1994 The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene. Cell, 77, 579-586.

Marsault, R. and Frelin, C. 1992 Activation by nitric oxide of guanylate cyclase in endothelial cells from brain capillaries. J Neurochem, 59, 942-945.

Martin, S., Botto, J.M., Vincent, J.P. and Mazella, J. 1999 Pivotal role of an aspartate residue in sodium sensitivity and coupling to G proteins of neurotensin receptors. Mol Pharmacol, 55, 210-215.

Mazella, J., Amar, S., Bozou, J.C., Kitabgi, P. and Vincent, J.P. 1987 Functional properties and molecular structure of central and peripheral neurotensin receptors. J Recept Res, 7, 157-165.

Mazella, J., Botto, J.M., Guillemare, E., Coppola, T., Sarret, P. and Vincent, J.P. 1996 Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain. J Neurosci, 16, 5613-5620.

Mazella, J., Chabry, J., Kitabgi, P. and Vincent, J.P. 1988 Solubilization and characterization of active neurotensin receptors from mouse brain. J Biol Chem, 263, 144-149.

Mazella, J., Chabry, J., Zsurger, N. and Vincent, J.P. 1989 Purification of the neurotensin receptor from mouse brain by affinity chromatography. J Biol Chem, 264, 5559-5563.

Mazella, J., Kwan, C.Y., Kitabgi, P. and Vincent, J.P. 1985 Covalent labeling of neurotensin receptors in rat gastric fundus plasma membranes. Peptides, 6, 1137-1141.

Mazella, J., Leonard, K., Chabry, J., Kitabgi, P., Vincent, J.P. and Beaudet, A. 1991 Binding and internalization of iodinated neurotensin in neuronal cultures from embryonic mouse brain. Brain Res, 564, 249-255.

Mazella, J., Poustis, C., Labbe, C., Checler, F., Kitabgi, P., Granier, C., van Rietschoten, J. and Vincent, J.P. 1983 Monoiodo-[Trp¹¹]neurotensin, a highly radioactive ligand of neurotensin receptors. Preparation, biological activity, and binding properties to rat brain synaptic membranes. J Biol Chem, 258, 3476-3481.

Mazella, J., Zsurger, N., Navarro, V., Chabry, J., Kaghad, M., Caput, D., Ferrara, P., Vita, N., Gully, D., Maffrand, J.P. and Vincent, J.P. 1998 The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor. J Biol Chem, 273, 26273-26276.

McKinney, M., Bolden, C., Smith, C., Johnson, A. and Richelson, E. 1990 Selective blockade of receptor-mediated cyclic GMP formation in N1E-115 neuroblastoma cells by an inhibitor of nitric oxide synthesis. Eur J Pharmacol, 178, 139-140.

Mendez, M., Souaze, F., Nagano, M., Kelly, P.A., Rostene, W. and Forgez, P. 1997 High affinity neurotensin receptor mRNA distribution in rat brain and peripheral tissues. Analysis by quantitative RT-PCR. J Mol Neurosci, 9, 93-102.

Morris, N.J., Ross, S.A., Lane, W.S., Moestrup, S.K., Petersen, C.M., Keller, S.R. and Lienhard, G.E. 1998 Sortilin is the major 110-kDa protein in GLUT4 vesicles from adipocytes. J Biol Chem, 273, 3582-3587.

Munck Petersen, C., Nielsen, M.S., Jacobsen, C., Tauris, J., Jacobsen, L., Gliemann, J., Moestrup, S.K. and Madsen, P. 1999 Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding. Embo J, 18, 595-604.

Najimi, M., Souaze, F., Mendez, M., Hermans, E., Berbar, T., Rostene, W. and Forgez, P. 1998 Activation of receptor gene transcription is required to maintain cell sensitization after agonist exposure. Study on neurotensin receptor. J Biol Chem, 273, 21634-21641.

Nakagawa, Y., Higashida, H. and Miki, N. 1984 A single class of neurotensin receptors with high affinity in neuroblastoma X glioma NG108-15 hybrid cells that mediate facilitation of synaptic transmission. J Neurosci, 4, 1653-1661.

Nemeroff, C.B., Bissette, G., Widerlov, E., Beckmann, H., Gerner, R., Manberg, P.J., Lindstrom, L., Prange, A.J., Jr. and Gattaz, W.F. 1989 Neurotensin-like immunoreactivity in cerebrospinal fluid of patients with schizophrenia, depression, anorexia nervosa-bulimia, and premenstrual syndrome. J Neuropsychiatry Clin Neurosci, 1, 16-20.

Nicot, A., Rostene, W. and Berod, A. 1994 Neurotensin receptor expression in the rat forebrain and midbrain: a combined analysis by in situ hybridization and receptor autoradiography. J Comp Neurol, 341, 407-419.

Nielsen, M.S., Jacobsen, C., Olivecrona, G., Gliemann, J. and Petersen, C.M. 1999 Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase. J Biol Chem, 274, 8832-8836.

Nouel, D., Faure, M.P., St Pierre, J.A., Alonso, R., Quirion, R. and Beaudet, A. 1997 Differential binding profile and internalization process of neurotensin via neuronal and glial receptors. J Neurosci, 17, 1795-1803.

Nouel, D., Sarret, P., Vincent, J.P., Mazella, J. and Beaudet, A. 1999 Pharmacological, molecular and functional characterization of glial neurotensin receptors. Neuroscience, 94, 1189-1197.

Nustede, R., Kohler, H., Pfannkuche, A., Folsch, U.R. and Schafmayer, A. 1989 The biological relevance of N-terminal neurotensin fragments in the regulation of exocrine pancreas secretion. Pancreas, 4, 114-119.

Ogura, C., Okuma, Y., Tamai, A. and Osumi, Y. 1989 Neurotensin potentiates the release of endogenous dopamine from the isolated rat retina. Biogenic Amines, 6, 253-262.

Ortego, J. and Coca-Prados, M. 1997 Molecular characterization and differential gene induction of the neuroendocrine-specific genes neurotensin, neurotensin receptor, PC1, PC2, and 7B2 in the human ocular ciliary epithelium. J Neurochem, 69, 1829-1839.

Osborne, N.N. 1986 Neurotensin in the retina : identification, release and receptor anlysis. Neurochem. Int., 9, 35-42.

Oury-Donat, F., Thurneyssen, O., Gonalons, N., Forgez, P., Gully, D., Le Fur, G. and Soubrie, P. 1995 Characterization of the effect of SR48692 on inositol monophosphate, cyclic GMP and cyclic AMP responses linked to neurotensin receptor activation in neuronal and non-neuronal cells. Br J Pharmacol, 116, 1899-1905.

J. M. Palacios, A. Pazos, M. M. Dietl, M. Schlumpf and W. Lichtensteiger, 1988, The ontogeny of brain neurotensin receptors studied by autoradiography, Neuroscience, 25, 1, 307-17

Pang, Y.P., Cusack, B., Groshan, K. and Richelson, E. 1996 Proposed ligand binding site of the transmembrane receptor for neurotensin(8-13). J Biol Chem, 271, 15060-15068.

Parker, I., Sumikawa, K. and Miledi, R. 1986 Neurotensin and substance P receptors expressed in Xenopus oocytes by messenger RNA from rat brain. Proc R Soc Lond B Biol Sci, 229, 151-159.

Petersen, C.M., Ellgaard, L., Nykjaer, A., Vilhardt, F., Vorum, H., Thogersen, H.C., Nielsen, M.S., Jacobsen, C., Moestrup, S.K. and Gliemann, J. 1996 The receptor-associated protein (RAP) binds calmodulin and is phosphorylated by calmodulin-dependent kinase II. Embo J, 15, 4165-4173.

Petersen, C.M., Nielsen, M.S., Nykjaer, A., Jacobsen, L., Tommerup, N., Rasmussen, H.H., Roigaard, H., Gliemann, J., Madsen, P. and Moestrup, S.K. 1997 Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography. J Biol Chem, 272, 3599-3605.

Pettibone, D.J. and Totaro, J.A. 1987 High affinity binding of [3H]neurotensin of rat uterus. Peptides, 8, 1169-1172.

Poustis, C., Mazella, J., Kitabgi, P. and Vincent, J.P. 1984 High-affinity neurotensin binding sites in differentiated neuroblastoma N1E115 cells. J Neurochem, 42, 1094-1100.

Quattrochi, J.J., Mc Bride, P.T. and Yates, A.J. 1985 Brainstem immaturity in SIDS : a quantitative rapid Golgi study of denditric spines in 95 infants. Brain Research, 325, 39-48.

Quirion, R., Gaudreau, P., St-Pierre, S. and Rioux, F. 1982a Localization of neurotensin binding sites in rat kidney. Peptides, 3, 765-769.

Quirion, R., Gaudreau, P., St-Pierre, S., Rioux, F. and Pert, C.B. 1982b Autoradiographic distribution of [3H]neurotensin receptors in rat brain: visualization by tritium-sensitive film. Peptides, 3, 757-763.

Radke, J.M., Owens, M.J., Ritchie, J.C. and Nemeroff, C.B. 1998 Atypical antipsychotic drugs selectively increase neurotensin efflux in dopamine terminal regions. Proc Natl Acad Sci U S A, 95, 11462-11464.

Richardson, A., Demoliou-Mason, C. and Barnard, E.A. 1992 Guanine nucleotide-binding protein-coupled and -uncoupled states of opioid receptors and their relevance to the determination of subtypes. Proc Natl Acad Sci U S A, 89, 10198-10202.

Sadoul, J.L., Checler, F., Kitabgi, P., Rostene, W., Javoy-Agid, F. and Vincent, J.P. 1984a Loss of high affinity neurotensin receptors in substantia nigra from parkinsonian subjects. Biochem Biophys Res Commun, 125, 395-404.

Sadoul, J.L., Kitabgi, P., Rostene, W., Javoy-Agid, F., Agid, Y. and Vincent, J.P. 1984b Characterization and visualization of neurotensin binding to receptor sites in human brain. Biochem Biophys Res Commun, 120, 206-213.

Sadoul, J.L., Mazella, J., Amar, S., Kitabgi, P. and Vincent, J.P. 1984c Preparation of neurotensin selectively iodinated on the tyrosine 3 residue. Biological activity and binding properties on mammalian neurotensin receptors. Biochem Biophys Res Commun, 120, 812-819.

Sarret, P., Beaudet, A., Vincent, J.P. and Mazella, J. 1998 Regional and cellular distribution of low affinity neurotensin receptor mRNA in adult and developing mouse brain. J Comp Neurol, 394, 344-356.

Sarrieau, A., Javoy-Agid, F., Kitabgi, P., Dussaillant, M., Vial, M., Vincent, J.P., Agid, Y. and Rostene, W.H. 1985 Characterization and autoradiographic distribution of neurotensin binding sites in the human brain. Brain Res, 348, 375-380.

Sato, M., Shiosaka, S. and Tohyama, M. 1991 Neurotensin and neuromedin N elevate the cytosolic calcium concentration via transiently appearing neurotensin binding sites in cultured rat cortex cells. Brain Res Dev Brain Res, 58, 97-103.

Scarceriaux, V., Souaze, F., Bachelet, C.M., Forgez, P., Bourdel, E., Martinez, J., Rostene, W. and Pelaprat, D. 1996 Neurotensin receptor down-regulation induced by dexamethasone and forskolin in rat hypothalamic cultures is mediated by endogenous neurotensin. J Neuroendocrinol, 8, 587-593.

Schotte, A. and Laduron, P.M. 1987 Different postnatal ontogeny of two [3H]neurotensin binding sites in rat brain. Brain Res, 408, 326-328.

Schotte, A., Leysen, J.E. and Laduron, P.M. 1986 Evidence for a displaceable non-specific [3H]neurotensin binding site in rat brain. Naunyn Schmiedebergs Arch Pharmacol, 333, 400-405.

Schotte, A., Rostene, W. and Laduron, P.M. 1988 Different subcellular localization of neurotensin-receptor and neurotensin-acceptor sites in the rat brain dopaminergic system. J Neurochem, 50, 1026-1031.

Seybold, V.S., Treder, B.G., Aanonsen, L.M., Parsons, A. and Brown, D.R. 1990 Neurotensin binding sites in porcine jejunum: biochemical characterization and intramural localization. Synapse, 6, 81-90.

Slusher, B.S., Zacco, A.E., Maslanski, J.A., Norris, T.E., McLane, M.W., Moore, W.C., Rogers, N.E. and Ignarro, L.J. 1994 The cloned neurotensin receptor mediates cyclic GMP formation when coexpressed with nitric oxide synthase cDNA. Mol Pharmacol, 46, 115-121.

Smit, M.J., Leurs, R., Alewijnse, A.E., Blauw, J., Van Nieuw Amerongen, G.P., Van De Vrede, Y., Roovers, E. and Timmerman, H. 1996 Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors. Proc Natl Acad Sci U S A, 93, 6802-6807.

Sotty, F., Brun, P., Leonetti, M., Steinberg, R., Soubrie, P., Renaud, B. and Suaud-Chagny, M.F. 2000 Comparative effects of neurotensin, neurotensin(8-13) and [D-Tyr(11)]neurotensin applied into the ventral tegmental area on extracellular dopamine in the rat prefrontal cortex and nucleus accumbens. Neuroscience, 98, 485-492.

Souaze, F., Rostene, W. and Forgez, P. 1997 Neurotensin agonist induces differential regulation of neurotensin receptor mRNA. Identification of distinct transcriptional and post-transcriptional mechanisms. J Biol Chem, 272, 10087-10094.

Szigethy, E., Leonard, K. and Beaudet, A. 1990 Ultrastructural localization of [¹²⁵I]neurotensin binding sites to cholinergic neurons of the rat nucleus basalis magnocellularis. Neuroscience, 36, 377-391.

Tanaka, K., Masu, M. and Nakanishi, S. 1990 Structure and functional expression of the cloned rat neurotensin receptor. Neuron, 4, 847-854.

Tavares, D., Tully, K. and Dobner, P.R. 1999 Sequences required for induction of neurotensin receptor gene expression during neuronal differentiation of N1E-115 neuroblastoma cells. J Biol Chem, 274, 30066-30079.

Trimble, E.R., Shaw, C., Bruzzone, R., Gjinovci, A. and Buchanan, K.D. 1987 Direct stimulation of enzyme secretion from rat exocrine pancreas by neurotensin and its naturally occurring fragments. Gastroenterology, 92, 699-703.

Trudeau, L.E. 2000 Neurotensin regulates intracellular calcium in ventral tegmental area astrocytes: evidence for the involvement of multiple receptors. Neuroscience, 97, 293-302.

Tucek, S. 1997 is the R and R* dichotomy real? TiPS, 18, 414-416.

Turner, J.T., James-Kracke, M.R. and Camden, J.M. 1990 Regulation of the neurotensin receptor and intracellular calcium mobilization in HT29 cells. J Pharmacol Exp Ther, 253, 1049-1056.

Uhl, G.R., Bennett, J.P., Jr. and Snyder, S.H. 1977 Neurotensin, a central nervous system peptide: apparent receptor binding in brain membranes. Brain Res, 130, 299-313.

Vandenbulcke, F., Nouel, D., Vincent, J., Mazella, J. and Beaudet, A. 2000 Ligand-induced internalization of neurotensin in transfected COS-7 cells: differential intracellular trafficking of ligand and receptor. J Cell Sci, 113, 2963-2975.

Vanisberg, M.A., Maloteaux, J.M., Octave, J.N. and Laduron, P.M. 1991 Rapid agonist-induced decrease of neurotensin receptors from the cell surface in rat cultured neurons. Biochem Pharmacol, 42, 2265-2274.

Vincent, J.P., Mazella, J., Chabry, J. and Zsürger, N. 1990 The neurotensin receptor from mammalian Brain - Solubilisation and purification by affinity chromatography. In Press, H. (ed.) Receptor purification, Vol. 1, pp. 131-145.

Vincent, J.P., Mazella, J. and Kitabgi, P. 1999 Neurotensin and neurotensin receptors. Trends Pharmacol Sci, 20, 302-309.

Vita, N., Laurent, P., Lefort, S., Chalon, P., Dumont, X., Kaghad, M., Gully, D., Le Fur, G., Ferrara, P. and Caput, D. 1993 Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor. FEBS Lett, 317, 139-142.

Vita, N., Oury-Donat, F., Chalon, P., Guillemot, M., Kaghad, M., Bachy, A., Thurneyssen, O., Garcia, S., Poinot-Chazel, C., Casellas, P., Keane, P., Le Fur, G., Maffrand, J.P., Soubrie, P., Caput, D. and Ferrara, P. 1998 Neurotensin is an antagonist of the human neurotensin NT2 receptor expressed in Chinese hamster ovary cells. Eur J Pharmacol, 360, 265-272.

Vizi, E.S. and Kiss, J.P. 1998 Neurochemistry and pharmacology of the major hippocampal transmitter systems: synaptic and nonsynaptic interactions [see comments]. Hippocampus, 8, 566-607.

Walker, N., Lepee-Lorgeoux, I., Fournier, J., Betancur, C., Rostene, W., Ferrara, P. and Caput, D. 1998 Tissue distribution and cellular localization of the levocabastine-sensitive neurotensin receptor mRNA in adult rat brain. Brain Res Mol Brain Res, 57, 193-200.

Watson, M., Isackson, P.J., Makker, M., Yamada, M.S., Yamada, M., Cusack, B. and Richelson, E. 1993 Identification of a polymorphism in the human neurotensin receptor gene. Mayo Clin Proc, 68, 1043-1048.

Watson, M.A., Yamada, M., Cusack, B., Veverka, K., Bolden-Watson, C. and Richelson, E. 1992 The rat neurotensin receptor expressed in Chinese hamster ovary cells mediates the release of inositol phosphates. J Neurochem, 59, 1967-1970.

Weiss, S., Schmidt, B.H., Sebben, M., Kemp, D.E., Bockaert, J. and Sladeczek, F. 1988 Neurotransmitter-induced inositol phosphate formation in neurons in primary culture. J Neurochem, 50, 1425-1433.

Wolf, S.S., Hyde, T.M., Saunders, R.C., Herman, M.M., Weinberger, D.R. and Kleinman, J.E. 1995 Autoradiographic characterization of neurotensin receptors in the entorhinal cortex of schizophrenic patients and control subjects. J Neural Transm Gen Sect, 102, 55-65.

Yamada, M., Bolden-Watson, C., Watson, M.A., Cho, T., Coleman, N.J. and Richelson, E. 1995 Regulation of neurotensin receptor mRNA expression by the receptor antagonist SR 48692 in the rat midbrain dopaminergic neurons. Brain Res Mol Brain Res, 33, 343-346.

Yamada, M., Lombet, A., Forgez, P. and Rostene, W. 1998 Distinct functional characteristics of levocabastine sensitive rat neurotensin NT2 receptor expressed in Chinese hamster ovary cells. Life Sci, 62, 375-380.

Yamada, M., Watson, M.A. and Richelson, E. 1993 Neurotensin stimulates cyclic AMP formation in CHO-rNTR-10 cells expressing the cloned rat neurotensin receptor. Eur J Pharmacol, 244, 99-101.

Yamada, M., Watson, M.A. and Richelson, E. 1994 Deletion mutation in the putative third intracellular loop of the rat neurotensin receptor abolishes polyphosphoinositide hydrolysis but not cyclic AMP formation in CHO-K1 cells. Mol Pharmacol, 46, 470-476.

Young, W.S.d. and Kuhar, M.J. 1981 Neurotensin receptor localization by light microscopic autoradiography in rat brain. Brain Res, 206, 273-285.

Zsürger, N., Chabry, J., Coquerel, A. and Vincent, J.P. 1992 Ontogenesis and binding properties of high-affinity neurotensin receptors in human brain. Brain Res, 586, 303-310.

Zsürger, N., Mazella, J. and Vincent, J.P. 1994 Solubilization and purification of a high affinity neurotensin receptor from newborn human brain. Brain Res, 639, 245-252.