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Mécanismes de la signalisation médiée par les récepteurs couplés aux protéines-G.

Auteur : Dr. Philippe SARRET - CNRS UPR 411 - Sophia Antipolis, France.

Institut et Hôpital Neurologique de Montréal, Université McGill - Montréal, Québec, Canada.


ARTICLES :

Article I : Sarret P., Botto J-M., Vincent J-P., Mazella J. and Beaudet A. (1998a). Preferential expression of sst2A over sst2B somatostatin receptor splice variant in rat brain and pituitary. Neuroendocrinology. 68, 37-43.

Article II : Stroh T., Jackson A.C., Sarret P., Dal Farra C., Vincent J-P., Kreienkamp H-J., Mazella J. and Beaudet A. (2000). Intracellular dynamics of sst5 receptors in transfected COS-7 cells: maintenance of cell surface receptors during ligand-induced endocytosis. Endocrinology. 141, 354-365.

Article III : Sarret P., Nouel D., Dal Farrra C., Vincent J-P., Beaudet A. and Mazella J. (1999). Receptor-mediated internalization is critical for the inhibition of the expression of growth hormone by somatostatin in the pituitary cell line AtT-20. J. Biol. Chem. 274, 19294-19300.

Article IV : Boudin H., Sarret P., Mazella J., Schonbrunn A., Beaudet A. (2000). Somatostatin-induced regulation of SST2A receptor expression and cell surface availability in central neurons : Role of receptor internalization. (soumis pour publication).

Article V : Mazella J., Botto J-M., Guillemare E., Coppola T., Sarret P. and Vincent J-P. (1996). Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain. J. Neurosci. 16, 5613-5620.

Article VI : Botto J.M., Sarret P., Vincent J-P. and Mazella J. (1997a). Identification and expression of a variant isoform of the levocabastine-sensitive neurotensin receptor in the mouse central nervous system. FEBS Lett. 400, 211-214.

Article VII : Botto J-M., Chabry J., Sarret P., Vincent J-P. and Mazella J. (1998). Stable expression of the mouse levocabastine-sensitive neurotensin receptor in HEK 293 cell line. Binding properties, photoaffinity labeling and internalization mechanism. Biochem. Biophys. Res. Commun. 243, 585-590.

Article VIII : Sarret P., Beaudet A., Vincent J-P. and Mazella J. (1998b). Regional and cellular distribution of the low affinity neurotensin receptor mRNA in adult and developing mouse brain. J. Comp. Neurol. 394, 344-356.

Article IX : Nouel D., Sarret P., Vincent J-P., Mazella J. and Beaudet A. (1999). Pharmacological, molecular and functionnal characterization of glial neurotensin receptors. Neuroscience. 94, 1189-1197.

Article X : Dubuc I., Sarret P., Labbé-Jullié C., Botto J-M., Honoré E., Bourdel E., Martinez J., Costentin J., Vincent J-P., Kitabgi P. and Mazella J. (1999a). Identification of the receptor subtype involved in the analgesic effect of neurotensin. J. Neurosci. 19, 503-510.

Avant-Propos   |    Introduction   |    I   |    II   |    III   |    IV   |    Conclusions et Perspectives   |    Bibliographie
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