accueil  >  revues  >  mécanismes moléculaires de la perception olfactive

Les mécanismes moléculaires de la perception olfactive.

Auteur : Dr. Valéry MATARAZZO - CNRS UPR 9024 - Laboratoire de Neurobiologie - Marseille, France.

Adresse actuelle : Johns Hopkins Medical Institute - Department of Neurosciences, Baltimore, MD, USA -

Références Bibliographiques :

A :

Alaoui-Ismaili, O., Robin, O., Rada, H., Dittmar, A. and Vernet-Maury, E. (1997). Basic emotions evoked by odorants: comparison between autonomic responses and self-evaluation. Physiology & Behavior, 62, (4), 713-20.

Amoore, J. E. (1971). Stereochemical and vibrational theories of odour. Nature, 233, (5317), 270-1.

Amoore, J. E., Johnston, J. W. and Rubin, M. (1964). The stereochemical theory of odor. Sciences American, 210, (2), 42-49.

Anderson, P. A. and Ache, B. W. (1985). Voltage- and current-clamp recordings of the receptor potential in olfactory receptor cells in situ. Brain Research, 338, (2), 273-80.

Asai, H., Kasai, H., Matsuda, Y., Yamazaki, N., Nagawa, F., Sakano, H. and Tsuboi, A. (1996). Genomic structure and transcription of a murine odorant receptor gene: differential initiation of transcription in the olfactory and testicular cells. Biochemical & Biophysical Research Communications, 221, (2), 240-7.

Astic, L., Pellier-Monnin, V. and Godinot, F. (1998). Spatio-temporal patterns of ensheathing cell differentiation in the rat olfactory system during development. Neuroscience, 84, (1), 295-307.

Astic, L. and Saucier, D. (1986). Anatomical mapping of the neuroepithelial projection to the olfactory bulb in the rat. Brain Research Bulletin, 16, (4), 445-54.

Avanzini, F., Bignetti, E., Bordi, C., Carfagna, G., Cavaggioni, A., Ferrari, G., Sorbi, R. T. and Tirindelli, R. (1987). Immunocytochemical localization of pyrazine-binding protein in bovine nasal mucosa. Cell & Tissue Research, 247, (2), 461-4.

B :

Bakalyar, H. A. and Reed, R. R. (1990). Identification of a specialized adenylyl cyclase that may mediate odorant detection. Science, 250, (4986), 1403-6.

Baker, H., Grillo, M. and Margolis, F. L. (1989). Biochemical and immunocytochemical characterization of olfactory marker protein in the rodent central nervous system. Journal of Comparative Neurology, 285, (2), 246-61.

Balasubramanian, S., Lynch, J. W. and Barry, P. H. (1996). Calcium-dependent modulation of the agonist affinity of the mammalian olfactory cyclic nucleotide-gated channel by calmodulin and a novel endogenous factor. Journal of Membrane Biology, 152, (1), 13-23.

Baldaccini, N. E., Gagliardo, A., Pelosi, P. and Topazzini, A. (1986). Occurrence of a pyrazine binding protein in the nasal mucosa of some vertebrates. Comparative Biochemistry & Physiology - B: Comparative Biochemistry, 84, (3), 249-53.

Barber, P. C. (1982). Neurogenesis and regeneration in the primary olfactory pathway of mammals. Bibliotheca Anatomica, (23), 12-25.

Barber, P. C. and Dahl, D. (1987). Glial fibrillary acidic protein (GFAP)-like immunoreactivity in normal and transected rat olfactory nerve. Experimental Brain Research, 65, (3), 681-5.

Barber, P. C. and Lindsay, R. M. (1982). Schwann cells of the olfactory nerves contain glial fibrillary acidic protein and resemble astrocytes. Neuroscience, 7, (12), 3077-90.

Bargmann, C. I. (1998). Neurobiology of the Caenorhabditis elegans genome. Science, 282, (5396), 2028-33.

Baude, E. J., Arora, V. K., Yu, S., Garbers, D. L. and Wedel, B. J. (1997). The cloning of a Caenorhabditis elegans guanylyl cyclase and the construction of a ligand-sensitive mammalian/nematode chimeric receptor. Journal of Biological Chemistry, 272, (25), 16035-9.

Belluscio, L., Gold, G. H., Nemes, A. and Axel, R. (1998). Mice deficient in G(olf) are anosmic. Neuron, 20, (1), 69-81.

Ben-Arie, N., Lancet, D., Taylor, C., Khen, M., Walker, N., Ledbetter, D. H., Carrozzo, R., Patel, K., Sheer, D. and Lehrach, H. (1994). Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire. Human Molecular Genetics, 3, (2), 229-35.

Bianchet, M. A., Bains, G., Pelosi, P., Pevsner, J., Snyder, S. H., Monaco, H. L. and Amzel, L. M. (1996). The three-dimensional structure of bovine odorant binding protein and its mechanism of odor recognition [see comments]. Nature Structural Biology, 3, (11), 934-9.

Bignetti, E., Cavaggioni, A., Pelosi, P., Persaud, K. C., Sorbi, R. T. and Tirindelli, R. (1985). Purification and characterisation of an odorant-binding protein from cow nasal tissue. European Journal of Biochemistry, 149, (2), 227-31.

Bishop, J. O., Clark, A. J., Clissold, P. M., Hainey, S. and Francke, U. (1982). Two main groups of mouse major urinary protein genes, both largely located on chromosome 4. EMBO Journal, 1, (5), 615-20.

Blache, P., Gros, L., Salazar, G. and Bataille, D. (1998). Cloning and tissue distribution of a new rat olfactory receptor-like (OL2). Biochemical & Biophysical Research Communications, 242, (3), 669-72.

Blomhoff, R., Green, M. H., Berg, T. and Norum, K. R. (1990). Transport and storage of vitamin A. Science, 250, (4979), 399-404.

Bockaert, J. and Pin, J. P. (1998). Utiliser un récepteur couplé aux protéines G pour communiquer. Un succès évolutif. Compte Rendu Acadademie des Sciences, Paris, 321, 529-620.

Boekhoff, I., Inglese, J., Schleicher, S., Koch, W. J., Lefkowitz, R. J. and Breer, H. (1994). Olfactory desensitization requires membrane targeting of receptor kinase mediated by beta gamma-subunits of heterotrimeric G proteins. Journal of Biological Chemistry, 269, (1), 37-40.

Boekhoff, I., Schleicher, S., Strotmann, J. and Breer, H. (1992). Odor-induced phosphorylation of olfactory cilia proteins. Proceedings of the National Academy of Sciences of the United States of America, 89, (24), 11983-7.

Boekhoffa, I., Strotmann, J., Raming, K., Tareilus, E. and Breer, H. (1990). Odorant-sensitive phospholipase C in insect antennae. Cellular Signalling, 2, (1), 49-56.

Boekhoffb, I., Tareilus, E., Strotmann, J. and Breer, H. (1990). Rapid activation of alternative second messenger pathways in olfactory cilia from rats by different odorants. EMBO Journal, 9, (8), 2453-8.

Bonigk, W., Bradley, J., Muller, F., Sesti, F., Boekhoff, I., Ronnett, G. V., Kaupp, U. B. and Frings, S. (1999). The native rat olfactory cyclic nucleotide-gated channel is composed of three distinct subunits. Journal of Neuroscience, 19, (13), 5332-47.

Boudjelal, M., Sivaprasadarao, A. and Findlay, J. B. (1996). Membrane receptor for odour-binding proteins. Biochemical Journal, 317, (Pt 1), 23-7.

Bouvier, M., Nantel, F., Valiquette, M., Moffett, S. and Mouillac, B. (1995). Le récepteur b2-adrénergique. Un modèle d'étude des mécanismes moléculaires de la désensibilisation. Médecine/sciences, 11, 819-827.

Bozza, T. C. and Kauer, J. S. (1998). Odorant response properties of convergent olfactory receptor neurons. Journal of Neuroscience, 18, (12), 4560-9.

Bradley, J., Li, J., Davidson, N., Lester, H. A. and Zinn, K. (1994). Heteromeric olfactory cyclic nucleotide-gated channels: a subunit that confers increased sensitivity to cAMP. Proceedings of the National Academy of Sciences of the United States of America, 91, (19), 8890-4.

Breer, H. (1991). Molecular reaction cascades in olfactory signal transduction. Journal of Steroid Biochemistry & Molecular Biology, 39, (4B), 621-5.

Breer, H. (1994). Odor recognition and second messenger signaling in olfactory receptor neurons. Seminars in Cell Biology, 5, (1), 25-32.

Breer, H. and Boekhoff, I. (1992). Second messenger signalling in olfaction. Current Opinion in Neurobiology, 2, (4), 439-43.

Breer, H., Boekhoff, I. and Tareilus, E. (1990). Rapid kinetics of second messenger formation in olfactory transduction. Nature, 345, (6270), 65-8.

Breer, H., Krieger, J., Meinken, C., Kiefer, H. and Strotmann, J. (1998). Expression and functional analysis of olfactory receptors. Annals of the New York Academy of Sciences, 855, 175-81.

Breipohl W., Mackay-Sim A., Grandt D., Rehn B. and C, D. (1986) In Ontogeny of Olfaction(Breipohl, W., ed.), Springer-Verlag, Berlin, pp. 21-33.

Briand, L., Nespoulous, C., Perez, V., Remy, J. J., Huet, J. C. and Pernollet, J. C. (2000). Ligand-binding properties and structural characterization of a novel rat odorant-binding protein variant. European Journal of Biochemistry, 267, (10), 3079-89.

Bronshtein, A. A. and A.V., M. (1974). Signifance of cilia and their motility in the functioning of olfactory receptors. Doklady Akademii Nauk SSSR., 213, 557-559.

Brownlow, S. and Sawyer, L. (1996). Waiting to inhale [news; comment]. Nature Structural Biology, 3, (11), 902-6.

Brunet, L. J., Gold, G. H. and Ngai, J. (1996). General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel. Neuron, 17, (4), 681-93.

Buck, L. and Axel, R. (1991). A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell, 65, (1), 175-87.

Buck, L. B. (1992). The olfactory multigene family. Current Opinion in Neurobiology, 2, (3), 282-8.

Buck, L. B. (2000). The molecular architecture of odor and pheromone sensing in mammals [comment]. Cell, 100, (6), 611-8.

Buiakova, O. I., Baker, H., Scott, J. W., Farbman, A., Kream, R., Grillo, M., Franzen, L., Richman, M., Davis, L. M., Abbondanzo, S., Stewart, C. L. and Margolis, F. L. (1996). Olfactory marker protein (OMP) gene deletion causes altered physiological activity of olfactory sensory neurons. Proceedings of the National Academy of Sciences of the United States of America, 93, (18), 9858-63.

Buiakova, O. I., Krishna, N. S., Getchell, T. V. and Margolis, F. L. (1994). Human and rodent OMP genes: conservation of structural and regulatory motifs and cellular localization. Genomics, 20, (3), 452-62.

Bulfone, A., Wang, F., Hevner, R., Anderson, S., Cutforth, T., Chen, S., Meneses, J., Pedersen, R., Axel, R. and Rubenstein, J. L. (1998). An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons. Neuron, 21, (6), 1273-82.

Bulger, M., van Doorninck, J. H., Saitoh, N., Telling, A., Farrell, C., Bender, M. A., Felsenfeld, G., Axel, R. and Groudine, M. (1999). Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes [published erratum appears in Proc Natl Acad Sci U S A 1999 Jul 6;96(14):8307]. Proceedings of the National Academy of Sciences of the United States of America, 96, (9), 5129-34.

Burchell, B. (1991). Turning on and turning off the sense of smell [news]. Nature, 350, (6313), 16-7.

Burd, G. D. (1992). Development of the olfactory nerve in the clawed frog, Xenopus laevis: II. Effects of hypothyroidism. Journal of Comparative Neurology, 315, (3), 255-63.

Burova, T. V., Choiset, Y., Jankowski, C. K. and Haertle, T. (1999). Conformational stability and binding properties of porcine odorant binding protein. Biochemistry, 38, (45), 15043-51.

C :

Caggiano, M., Kauer, J. S. and Hunter, D. D. (1994). Globose basal cells are neuronal progenitors in the olfactory epithelium: a lineage analysis using a replication-incompetent retrovirus. Neuron, 13, (2), 339-52.

Calof, A. L. (1995). Intrinsic and extrinsic factors regulating vertebrate neurogenesis. Current Opinion in Neurobiology, 5, (1), 19-27.

Calof, A. L. and Chikaraishi, D. M. (1989). Analysis of neurogenesis in a mammalian neuroepithelium: proliferation and differentiation of an olfactory neuron precursor in vitro. Neuron, 3, (1), 115-27.

Calof, A. L., Hagiwara, N., Holcomb, J. D., Mumm, J. S. and Shou, J. (1996). Neurogenesis and cell death in olfactory epithelium. Journal of Neurobiology, 30, (1), 67-81.

Calofa, A. L., Mumm, J. S., Rim, P. C. and Shou, J. (1998). The neuronal stem cell of the olfactory epithelium. Journal of Neurobiology, 36, (2), 190-205.

Calofb, A. L., Rim, P. C., Askins, K. J., Mumm, J. S., Gordon, M. K., Iannuzzelli, P. and Shou, J. (1998). Factors regulating neurogenesis and programmed cell death in mouse olfactory epithelium. Annals of the New York Academy of Sciences, 855, 226-9.

Cambray-Deakin, M. A. (1991) In The Neuronal Cytoskeleton(Burgoyne and Wiley-Liss, ed.), Brisbane, pp. 233-255.

Cancalon, P. (1982). Degeneration and regeneration of olfactory cells induced by ZnSO4 and other chemicals. Tissue & Cell, 14, (4), 717-33.

Cau, E., Gradwohl, G., Fode, C. and Guillemot, F. (1997). Mash1 activates a cascade of bHLH regulators in olfactory neuron progenitors. Development, 124, (8), 1611-21.

Cavaggioni, A., Findlay, J. B. and Tirindelli, R. (1990). Ligand binding characteristics of homologous rat and mouse urinary proteins and pyrazine-binding protein of calf. Comparative Biochemistry & Physiology - B: Comparative Biochemistry, 96, (3), 513-20.

Chen, T. Y. and Yau, K. W. (1994). Direct modulation by Ca(2+)-calmodulin of cyclic nucleotide-activated channel of rat olfactory receptor neurons. Nature, 368, (6471), 545-8.

Chess, A., Buck, L., Dowling, M. M., Axel, R. and Ngai, J. (1992). Molecular biology of smell: expression of the multigene family encoding putative odorant receptors. Cold Spring Harbor Symposia on Quantitative Biology, 57, 505-16.

Chess, A., Simon, I., Cedar, H. and Axel, R. (1994). Allelic inactivation regulates olfactory receptor gene expression. Cell, 78, (5), 823-34.

Chuah, M. I. and Au, C. (1991). Olfactory Schwann cells are derived from precursor cells in the olfactory epithelium. Journal of Neuroscience Research, 29, (2), 172-80.

Clyne, P. J., Warr, C. G., Freeman, M. R., Lessing, D., Kim, J. and Carlson, J. R. (1999). A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila [see comments]. Neuron, 22, (2), 327-38.

Conover, J. C. and Yancopoulos, G. D. (1997). Neurotrophin regulation of the developing nervous system: analyses of knockout mice. Reviews in the Neurosciences, 8, (1), 13-27.

Corcoran, L. M., Thompson, J. K., Walliker, D. and Kemp, D. J. (1988). Homologous recombination within subtelomeric repeat sequences generates chromosome size polymorphisms in P. falciparum. Cell, 53, (5), 807-13.

Costanzo, R. M. and Graziadei, P. P. (1983). A quantitative analysis of changes in the olfactory epithelium following bulbectomy in hamster. Journal of Comparative Neurology, 215, (4), 370-81.

Cremer, H., Lange, R., Christoph, A., Plomann, M., Vopper, G., Roes, J., Brown, R., Baldwin, S., Kraemer, P. and Scheff, S. (1994). Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning. Nature, 367, (6462), 455-9.

Cunningham, A. M., Ryugo, D. K., Sharp, A. H., Reed, R. R., Snyder, S. H. and Ronnett, G. V. (1993). Neuronal inositol 1,4,5-trisphosphate receptor localized to the plasma membrane of olfactory cilia. Neuroscience, 57, (2), 339-52.

D :

Dahmen, N., Wang, H. L. and Margolis, F. L. (1992). Expression of olfactory receptors in Xenopus oocytes. Journal of Neurochemistry, 58, (3), 1176-9.

Dal Monte, M., Andreini, I., Revoltella, R. and Pelosi, P. (1991). Purification and characterization of two odorant-binding proteins from nasal tissue of rabbit and pig. Comparative Biochemistry & Physiology - B: Comparative Biochemistry, 99, (2), 445-51.

Dal Monte, M., Centini, M., Anselmi, M. and Pelosi, P. (1993). Binding of selected odorantss to bovine and porcine odorant bining proteins. Chem.Senses, 18.

Davis, J. A. and Reed, R. R. (1996). Role of Olf-1 and Pax-6 transcription factors in neurodevelopment. Journal of Neuroscience, 16, (16), 5082-94.

Dawson, T. M., Arriza, J. L., Jaworsky, D. E., Borisy, F. F., Attramadal, H., Lefkowitz, R. J. and Ronnett, G. V. (1993). Beta-adrenergic receptor kinase-2 and beta-arrestin-2 as mediators of odorant-induced desensitization. Science, 259, (5096), 825-9.

De Lorenzo, A. J. (1957). Electron microscopicc observations of the olfactoy mucosa and olfactory nerve. J. biophys.Biochem.Cytol., 3, 839-850.

Dear, T. N., Campbell, K. and Rabbitts, T. H. (1991). Molecular cloning of putative odorant-binding and odorant-metabolizing proteins. Biochemistry, 30, (43), 10376-82.

DeHamer, M. K., Guevara, J. L., Hannon, K., Olwin, B. B. and Calof, A. L. (1994). Genesis of olfactory receptor neurons in vitro: regulation of progenitor cell divisions by fibroblast growth factors. Neuron, 13, (5), 1083-97.

Dexter, T. M. and Spooncer, E. (1987). Growth and differentiation in the hemopoietic system. Annual Review of Cell Biology, 3, 423-41.

Dhallan, R. S., Yau, K. W., Schrader, K. A. and Reed, R. R. (1990). Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons. Nature, 347, (6289), 184-7.

Dickinson, T. A., White, J., Kauer, J. S. and Walt, D. R. (1998). Current trends in 'artificial-nose' technology. Trends in Biotechnology, 16, (6), 250-8.

Ding, X. X., Koop, D. R., Crump, B. L. and Coon, M. J. (1986). Immunochemical identification of cytochrome P-450 isozyme 3a (P-450ALC) in rabbit nasal and kidney microsomes and evidence for differential induction by alcohol. Molecular Pharmacology, 30, (4), 370-8.

Drosophila Odorant Receptor Comitee. (2000). A unified nomenclature system for the Drosophila odorant receptors. Drosophila Odorant Receptor Nomenclature Committee. Cell, 102, (2), 145-146.

Drutel, G., Arrang, J. M., Diaz, J., Wisnewsky, C., Schwartz, K. and Schwartz, J. C. (1995). Cloning of OL1, a putative olfactory receptor and its expression in the developing rat heart. Receptors & Channels, 3, (1), 33-40.

Duchamp-Viret, P., Chaput, M. A. and Duchamp, A. (1999). Odor response properties of rat olfactory receptor neurons. Science, 284, (5423), 2171-4.

Dulac, C. (1997). How does the brain smell? Neuron, 19, (3), 477-80.

Dwyer, N. D., Troemel, E. R., Sengupta, P. and Bargmann, C. I. (1998). Odorant receptor localization to olfactory cilia is mediated by ODR-4, a novel membrane-associated protein. Cell, 93, (3), 455-66.

E :

Ebrahimi, F. A. and Chess, A. (1998). The specification of olfactory neurons. Current Opinion in Neurobiology, 8, (4), 453-7.

Ebrahimi, F. A. and Chess, A. (2000). Olfactory neurons are interdependent in maintaining axonal projections. Current Biology, 10, (4), 219-22.

Eide, F. F., Lowenstein, D. H. and Reichardt, L. F. (1993). Neurotrophins and their receptors--current concepts and implications for neurologic disease. Experimental Neurology, 121, (2), 200-14.

Eisthen, H. L. (1997). Evolution of vertebrate olfactory systems. Brain, Behavior & Evolution, 50, (4), 222-33.

Enjalbert, A. (1998). Récepteurs membranaires et mécanismes de transduction. médecine/Sciences, n░special, (décembre), 40-48.

F :

Fadool, D. A. and Ache, B. W. (1992). Plasma membrane inositol 1,4,5-trisphosphate-activated channels mediate signal transduction in lobster olfactory receptor neurons. Neuron, 9, (5), 907-18.

Fadool, D. A. and Ache, B. W. (1994). Inositol 1,3,4,5-tetrakisphosphate-gated channels interact with inositol 1,4,5-trisphosphate-gated channels in olfactory receptor neurons. Proceedings of the National Academy of Sciences of the United States of America, 91, (20), 9471-3.

Fadool, D. A., Estey, S. J. and Ache, B. W. (1995). Evidence that a Gq-protein mediates excitatory odor transduction in lobster olfactory receptor neurons. Chemical Senses, 20, (5), 489-98.

Farbman, A. I. (1990). Olfactory neurogenesis: genetic or environmental controls? Trends in Neurosciences, 13, (9), 362-5.

Farbman, A. I. and Squinto, L. M. (1985). Early development of olfactory receptor cell axons. Brain Research, 351, (2), 205-13.

Felicioli, A., Ganni, M., Garibotti, M. and Pelosi, P. (1993). Multiple types and forms of odorant-binding proteins in the Old-World porcupine Hystrix cristata. Comparative Biochemistry & Physiology - B: Comparative Biochemistry, 105, (3-4), 775-84.

Ferona, F., Mackay-Sim, A., Andrieu, J. L., Matthaei, K. I., Holley, A. and Sicard, G. (1999). Stress induces neurogenesis in non-neuronal cell cultures of adult olfactory epithelium. Neuroscience, 88, (2), 571-83.

Feronb, F., Vincent, A. and Mackay-Sim, A. (1999). Dopamine promotes differentiation of olfactory neuron in vitro. Brain Research, 845, (2), 252-9.

Ferrand, N., Pessah, M., Frayon, S., Marais, J. and Garel, J. M. (1999). Olfactory receptors, Golf alpha and adenylyl cyclase mRNA expressions in the rat heart during ontogenic development. Journal of Molecular & Cellular Cardiology, 31, (5), 1137-42.

Fesenko, E. E., Novoselov, V. I. and Krapivinskaya, L. D. (1979). Molecular mechanisms of olfactory reception. IV. Some biochemical characteristics of the camphor receptor from rat olfactory epithelium. Biochimica et Biophysica Acta, 587, (3), 424-32.

Flower, D. R. (1996). The lipocalin protein family: structure and function. Biochemical Journal, 318, (Pt 1), 1-14.

Freitag, J., Krieger, J., Strotmann, J. and Breer, H. (1995). Two classes of olfactory receptors in Xenopus laevis. Neuron, 15, (6), 1383-92.

Freitag, J., Ludwig, G., Andreini, I., Rossler, P. and Breer, H. (1998). Olfactory receptors in aquatic and terrestrial vertebrates. Journal of Comparative Physiology A-Sensory Neural & Behavioral Physiology, 183, (5), 635-50.

Friedrich, R. W. and Korsching, S. I. (1997). Combinatorial and chemotopic odorant coding in the zebrafish olfactory bulb visualized by optical imaging. Neuron, 18, (5), 737-52.

Frisch, D. (1967). Ultrastructure of mouse olfactory mucosa. American Journal of Anatomy, 121, (1), 87-120.

Fulle, H. J. and Garbers, D. L. (1994). Guanylyl cyclases: a family of receptor-linked enzymes. Cell Biochemistry & Function, 12, (3), 157-65.

Fulle, H. J., Vassar, R., Foster, D. C., Yang, R. B., Axel, R. and Garbers, D. L. (1995). A receptor guanylyl cyclase expressed specifically in olfactory sensory neurons. Proceedings of the National Academy of Sciences of the United States of America, 92, (8), 3571-5.

Furuta, Y., Piston, D. W. and Hogan, B. L. (1997). Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development. Development, 124, (11), 2203-12.

G :

Garbers, D. L. and Lowe, D. G. (1994). Guanylyl cyclase receptors. Journal of Biological Chemistry, 269, (49), 30741-4.

Garibotti, M., Navarrini, A., Pisanelli, A. M. and Pelosi, P. (1997). Three odorant-binding proteins from rabbit nasal mucosa. Chemical Senses, 22, (4), 383-90.

Gasser, H. S. (1956). Olfactory nerve fibers. Journal of General Physiology, 39, 473-496.

Gautier-Courteille, C., Salanova, M. and Conti, M. (1998). The olfactory adenylyl cyclase III is expressed in rat germ cells during spermiogenesis. Endocrinology, 139, (5), 2588-99.

Getchell, M. L. and Getchell, T. V. (1991). Immunohistochemical localization of components of the immune barrier in the olfactory mucosae of salamanders and rats. Anatomical Record, 231, (3), 358-74.

Getchell, T. V. (1977). Analysis of intracellular recordings from salamander olfactory epithelium. Brain Research, 123, (2), 275-86.

Getchell, T. V., Margolis, F. L. and Getchell, M. L. (1984). Perireceptor and receptor events in vertebrate olfaction. Progress in Neurobiology, 23, (4), 317-45.

Gheusi, G., Cremer, H., McLean, H., Chazal, G., Vincent, J. D. and Lledo, P. M. (2000). Importance of newly generated neurons in the adult olfactory bulb for odor discrimination. Proceedings of the National Academy of Sciences of the United States of America, 97, (4), 1823-8.

Gibson, A. D. and Garbers, D. L. (2000). Guanylyl cyclases as a family of putative odorant receptors. Annual Review of Neuroscience, 23, 417-39.

Gimelbrant, A. A., Haley, S. L. and McClintock, T. S. (2000). Olfactory receptor trafficking involves conserved regulatory steps. Journal of Biological Chemistry, Nov 1; [epub ahead of print].

Gimelbrant, A. A., Stoss, T. D., Landers, T. M. and McClintock, T. S. (1999). Truncation releases olfactory receptors from the endoplasmic reticulum of heterologous cells. Journal of Neurochemistry, 72, (6), 2301-11.

Gomez, G., Rawson, N. E., Cowart, B., Lowry, L. D., Pribitkin, E. A. and Restrepo, D. (2000). Modulation of odor-induced increases in [Ca(2+)](i) by inhibitors of protein kinases A and C in rat and human olfactory receptor neurons. Neuroscience, 98, (1), 181-9.

Gordon, M. K., Mumm, J. S., Davis, R. A., Holcomb, J. D. and Calof, A. L. (1995). Dynamics of MASH1 expression in vitro and in vivo suggest a non-stem cell site of MASH1 action in the olfactory receptor neuron lineage. Molecular & Cellular Neurosciences, 6, (4), 363-79.

Graham, A., Francis-West, P., Brickell, P. and Lumsden, A. (1994). The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest. Nature, 372, (6507), 684-6.

Graziadei, G. A. and Monti Graziadei, P. P. (1979). Neurogenesis and neuron regeneration in the olfactory system of mammals. II. Degeneration and reconstitution of the olfactory sensory neurons after axotomy. Journal of Neurocytology, 8, (2), 197-213.

Graziadei, P. P. and Metcalf, J. F. (1971). Autoradiographic and ultrastructural observations on the frog's olfactory mucosa. Zeitschrift Fur Zellforschung Und Mikroskopische Anatomie, 116, (3), 305-18.

Graziadei, P. P. C. and Monti Graziadei, G. A. (1978) In Handbook of Sensory Physiology, Vol. IX (Jacobson, M., ed.), Springer-Verlag, Berlin, pp. 55-82.

Griff, I. C. and Reed R. R. (1995). The genetic basis for specific anosmia to isovaleric acid in the mouse. Cell, 83: 407-414.

Guillemot, F., Lo, L. C., Johnson, J. E., Auerbach, A., Anderson, D. J. and Joyner, A. L. (1993). Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell, 75, (3), 463-76.

H :

Hatt, H. and Ache, B. W. (1994). Cyclic nucleotide- and inositol phosphate-gated ion channels in lobster olfactory receptor neurons [see comments]. Proceedings of the National Academy of Sciences of the United States of America, 91, (14), 6264-8.

Hatt, H., Gisselmann, G. and Wetzel, C. H. (1999). Cloning, functional expression and characterization of a human olfactory receptor. Cellular & Molecular Biology, 45, (3), 285-91.

Henzel, W. J., Rodriguez, H., Singer, A. G., Stults, J. T., Macrides, F., Agosta, W. C. and Niall, H. (1988). The primary structure of aphrodisin. Journal of Biological Chemistry, 263, (32), 16682-7.

Herent, M. F., Collin, S. and Pelosi, P. (1995). Affinities of nutty and green-smelling pyrazines and thiazoles to odorant-binding proteins, in relation with their lipophilicity. Chemical Senses, 20, (6), 601-8.

Herve, D., Levi-Strauss, M., Marey-Semper, I., Verney, C., Tassin, J. P., Glowinski, J. and Girault, J. A. (1993). G(olf) and Gs in rat basal ganglia: possible involvement of G(olf) in the coupling of dopamine D1 receptor with adenylyl cyclase. Journal of Neuroscience, 13, (5), 2237-48.

Herve, D., Rogard, M. and Levi-Strauss, M. (1995). Molecular analysis of the multiple Golf alpha subunit mRNAs in the rat brain. Brain Research. Molecular Brain Research, 32, (1), 125-34.

Hinds, J. W., Hinds, P. L. and McNelly, N. A. (1984). An autoradiographic study of the mouse olfactory epithelium: evidence for long-lived receptors. Anatomical Record, 210, (2), 375-83.

Holcomb, J. D., Mumm, J. S. and Calof, A. L. (1995). Apoptosis in the neuronal lineage of the mouse olfactory epithelium: regulation in vivo and in vitro. Developmental Biology (Orlando), 172, (1), 307-23.

Holley, A. and G., S. (1994). Les récepteurs olfactifs et le codage neuronal de l'odeur. Médecine/Science, 10, 1091-1098.

Honda, E., Teeter, J. H. and Restrepo, D. (1995). InsP3-gated ion channels in rat olfactory cilia membrane. Brain Research, 703, (1-2), 79-85.

Hopkins, A. E. (1926). The olfactory receptors in Vertebrates. Journal of Comparative Neurology, 41, 253-289.

Huque, T. and Bruch, R. C. (1986). Odorant- and guanine nucleotide-stimulated phosphoinositide turnover in olfactory cilia. Biochemical & Biophysical Research Communications, 137, (1), 36-42.

I :

Ingi, T. and Ronnett, G. V. (1995). Direct demonstration of a physiological role for carbon monoxide in olfactory receptor neurons. Journal of Neuroscience, 15, (12), 8214-22.

Issel-Tarver, L. and Rine, J. (1997). The evolution of mammalian olfactory receptor genes. Genetics, 145, (1), 185-95.

Ivic, L., Pyrski, M. M., Margolis, J. W., Richards, L. J., Firestein, S. and Margolis, F. L. (2000). Adenoviral vector-mediated rescue of the OMP-null phenotype in vivo. Nature Neurosciences, 11, 1113-1120.

J :

Jones, D. T. and Reed, R. R. (1989). Golf: an olfactory neuron specific-G protein involved in odorant signal transduction. Science, 244, (4906), 790-5.

Joshi, H., Getchell, M. L., Zielinski, B. and Getchell, T. V. (1987). Spectrophotometric determination of cation concentrations in olfactory mucus. Neuroscience Letters, 82, (3), 321-6.

Juilfs, D. M., Fulle, H. J., Zhao, A. Z., Houslay, M. D., Garbers, D. L. and Beavo, J. A. (1997). A subset of olfactory neurons that selectively express cGMP-stimulated phosphodiesterase (PDE2) and guanylyl cyclase-D define a unique olfactory signal transduction pathway. Proceedings of the National Academy of Sciences of the United States of America, 94, (7), 3388-95.

K :

Kalinoski, D. L., Aldinger, S. B., Boyle, A. G., Huque, T., Marecek, J. F., Prestwich, G. D. and Restrepo, D. (1992). Characterization of a novel inositol 1,4,5-trisphosphate receptor in isolated olfactory cilia. Biochemical Journal, 281, (Pt 2), 449-56.

Kang, J. and Caprio, J. (1995). In vivo responses of single olfactory receptor neurons in the channel catfish, Ictalurus punctatus. Journal of Neurophysiology, 73, (1), 172-7.

Karavanich, C. and Anholt, R. R. (1998). Evolution of olfactomedin. Structural constraints and conservation of primary sequence motifs. Annals of the New York Academy of Sciences, 855, 294-300.

Kauer, J. S. (1983). Surface morphology of olfactory receptors. Journal of Submicroscopic Cytology, 15, (1), 167-71.

Kiefer, H., Krieger, J., Olszewski, J. D., Von Heijne, G., Prestwich, G. D. and Breer, H. (1996). Expression of an olfactory receptor in Escherichia coli: purification, reconstitution, and ligand binding. Biochemistry, 35, (50), 16077-84.

Kim, M. S., Repp, A. and Smith, D. P. (1998). LUSH odorant-binding protein mediates chemosensory responses to alcohols in Drosophila melanogaster. Genetics, 150, (2), 711-21.

Kleene, S. J. (1993). Origin of the chloride current in olfactory transduction. Neuron, 11, (1), 123-32.

Kleene, S. J. and Gesteland, R. C. (1991). Calcium-activated chloride conductance in frog olfactory cilia. Journal of Neuroscience, 11, (11), 3624-9.

Kleene, S. J., Gesteland, R. C. and Bryant, S. H. (1994). An electrophysiological survey of frog olfactory cilia. Journal of Experimental Biology, 195, 307-28.

Kobilka, B. (1992). Adrenergic receptors as models for G protein-coupled receptors. Annual Review of Neuroscience, 15, 87-114.

Kramer, P. R., Krishnamurthy, R., Mitchell, P. J. and Wray, S. (2000). Transcription factor activator protein-2 is required for continued luteinizing hormone-releasing hormone expression in the forebrain of developing mice. Endocrinology, 141, (5), 1823-38.

Kramer, P. R. and Wray, S. (2000). Novel gene expressed in nasal region influences outgrowth of olfactory axons and migration of luteinizing hormone-releasing hormone (LHRH) neurons. Genes & Development, 14, (14), 1824-34.

Kramer, R. H. and Siegelbaum, S. A. (1992). Intracellular Ca2+ regulates the sensitivity of cyclic nucleotide-gated channels in olfactory receptor neurons. Neuron, 9, (5), 897-906.

Krautwurst, D., Yau, K. W. and Reed, R. R. (1998). Identification of ligands for olfactory receptors by functional expression of a receptor library. Cell, 95, (7), 917-26.

Krieger, J., Schleicher, S., Strotmann, J., Wanner, I., Boekhoff, I., Raming, K., De Geus, P. and Breer, H. (1994). Probing olfactory receptors with sequence-specific antibodies. European Journal of Biochemistry, 219, (3), 829-35.

Kubick, S., Strotmann, J., Andreini, I. and Breer, H. (1997). Subfamily of olfactory receptors characterized by unique structural features and expression patterns. Journal of Neurochemistry, 69, (2), 465-75.

Kurahashi, T. and Menini, A. (1997). Mechanism of odorant adaptation in the olfactory receptor cell [see comments]. Nature, 385, (6618), 725-9.

Kurahashi, T. and Shibuya, T. (1989). Membrane responses and permeability changes to odorants in the solitary olfactory receptors cells of newt. Zoological Sciences, 6, 19-30.

Kurahashi, T. and Shibuya, T. (1990). Ca2(+)-dependent adaptive properties in the solitary olfactory receptor cell of the newt. Brain Research, 515, (1-2), 261-8.

Kurahashi, T. and Yau, K. W. (1993). Co-existence of cationic and chloride components in odorant-induced current of vertebrate olfactory receptor cells. Nature, 363, (6424), 71-4.

L :

Lacazette, E., Gachon, A. M. and Pitiot, G. (2000). A novel human odorant-binding protein gene family resulting from genomic duplicons at 9q34: differential expression in the oral and genital spheres. Human Molecular Genetics, 9, (2), 289-301.

Lancet, D. (1994). Olfaction. Exclusive receptors [news]. Nature, 372, (6504), 321-2.

Lee, K. H., Wells, R. G. and Reed, R. R. (1987). Isolation of an olfactory cDNA: similarity to retinol-binding protein suggests a role in olfaction. Science, 235, (4792), 1053-6.

Lee, V. M. and Pixley, S. K. (1994). Age and differentiation-related differences in neuron-specific tubulin immunostaining of olfactory sensory neurons. Brain Research. Developmental Brain Research, 83, (2), 209-15.

Leinders-Zufall, T., Rand, M. N., Shepherd, G. M., Greer, C. A. and Zufall, F. (1997). Calcium entry through cyclic nucleotide-gated channels in individual cilia of olfactory receptor cells: spatiotemporal dynamics. Journal of Neuroscience, 17, (11), 4136-48.

Leinders-Zufall, T., Shepherd, G. M. and Zufall, F. (1996). Modulation by cyclic GMP of the odour sensitivity of vertebrate olfactory receptor cells. Proceedings of the Royal Society of London - Series B: Biological Sciences, 263, (1371), 803-11.

L'Etoile, N. D. and Bargmann, C. I. (2000). Olfaction and odor discrimination are mediated by the C. elegans guanylyl cyclase ODR-1 [see comments]. Neuron, 25, (3), 575-86.

Li, W., Cogswell, C. A. and LoTurco, J. J. (1998). Neuronal differentiation of precursors in the neocortical ventricular zone is triggered by BMP. Journal of Neuroscience, 18, (21), 8853-62.

Liman, E. R. and Buck, L. B. (1994). A second subunit of the olfactory cyclic nucleotide-gated channel confers high sensitivity to cAMP. Neuron, 13, (3), 611-21.

Lin, D. M., Wang, F., Lowe, G., Gold, G. H., Axel, R., Ngai, J. and Brunet, L. (2000). Formation of precise connections in the olfactory bulb occurs in the absence of odorant-evoked neuronal activity. Neuron, 26, (1), 69-80.

Lindsay, R. M., Wiegand, S. J., Altar, C. A. and DiStefano, P. S. (1994). Neurotrophic factors: from molecule to man. Trends in Neurosciences, 17, (5), 182-90.

Liu, M., Chen, T. Y., Ahamed, B., Li, J. and Yau, K. W. (1994). Calcium-calmodulin modulation of the olfactory cyclic nucleotide-gated cation channel [published erratum appears in Science 1994 Dec 23;266(5193):1933]. Science, 266, (5189), 1348-54.

Lo, L. C., Johnson, J. E., Wuenschell, C. W., Saito, T. and Anderson, D. J. (1991). Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells. Genes & Development, 5, (9), 1524-37.

Lobel, D., Marchese, S., Krieger, J., Pelosi, P. and Breer, H. (1998). Subtypes of odorant-binding proteins--heterologous expression and ligand binding. European Journal of Biochemistry, 254, (2), 318-24.

Lois, C. and Alvarez-Buylla, A. (1994). Long-distance neuronal migration in the adult mammalian brain. Science, 264, (5162), 1145-8.

Luskin, M. B. (1993). Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. Neuron, 11, (1), 173-89.

M :

Ma, L. and Michel, W. C. (1998). Drugs affecting phospholipase C-mediated signal transduction block the olfactory cyclic nucleotide-gated current of adult zebrafish. Journal of Neurophysiology, 79, (3), 1183-92.

Ma, M. and Shepherd, G. M. (2000). Functional mosaic organization of mouse olfactory receptor neurons. Proceedings National Acadademic Sciences U S A, 97, (23), 12869-12874.

Mackay-Sim, A. and Beard, M. D. (1987). Hypothyroidism disrupts neural development in the olfactory epithelium of adult mice. Brain Research, 433, (2), 190-8.

Mackay-Sim, A. and Kittel, P. (1991). Cell dynamics in the adult mouse olfactory epithelium: a quantitative autoradiographic study. Journal of Neuroscience, 11, (4), 979-84.

Magert, H. J., Cieslak, A., Alkan, O., Luscher, B., Kauffels, W. and Forssmann, W. G. (1999). The golden hamster aphrodisin gene. Structure, expression in parotid glands of female animals, and comparison with a similar murine gene. Journal of Biological Chemistry, 274, (1), 444-50.

Magert, H. J., Hadrys, T., Cieslak, A., Groger, A., Feller, S. and Forssmann, W. G. (1995). cDNA sequence and expression pattern of the putative pheromone carrier aphrodisin. Proceedings of the National Academy of Sciences of the United States of America, 92, (6), 2091-5.

Mahanthappa, N. K. and Schwarting, G. A. (1993). Peptide growth factor control of olfactory neurogenesis and neuron survival in vitro: roles of EGF and TGF-beta s. Neuron, 10, (2), 293-305.

Malnic, B., Hirono, J., Sato, T. and Buck, L. B. (1999). Combinatorial receptor codes for odors. Cell, 96, (5), 713-23.

Marin-Padilla, M. and Amieva, M. R. (1989). Early neurogenesis of the mouse olfactory nerve: Golgi and electron microscopic studies. Journal of Comparative Neurology, 288, (2), 339-52.

Matsuoka, I., Mori, T., Sato, T., Sakai, M. and Kurihara, K. (1995). Identification of novel guanylyl cyclases from chemosensory tissues of rat and cattle. Biochemical & Biophysical Research Communications, 216, (1), 242-8.

McClintock, T. S., Landers, T. M., Gimelbrant, A. A., Fuller, L. Z., Jackson, B. A., Jayawickreme, C. K. and Lerner, M. R. (1997). Functional expression of olfactory-adrenergic receptor chimeras and intracellular retention of heterologously expressed olfactory receptors. Brain Research. Molecular Brain Research, 48, (2), 270-8.

Menco, B. P. (1984). Ciliated and microvillous structures of rat olfactory and nasal respiratory epithelia. A study using ultra-rapid cryo-fixation followed by freeze-substitution or freeze-etching. Cell & Tissue Research, 235, (2), 225-41.

Menco, B. P. (1989). Electron-microscopic demonstration of olfactory-marker protein with protein G-gold in freeze-substituted, Lowicryl K11M-embedded rat olfactory-receptor cells. Cell & Tissue Research, 256, (2), 275-81.

Menco, B. P., Bruch, R. C., Dau, B. and Danho, W. (1992). Ultrastructural localization of olfactory transduction components: the G protein subunit Golf alpha and type III adenylyl cyclase. Neuron, 8, (3), 441-53.

Menco, B. P., Cunningham, A. M., Qasba, P., Levy, N. and Reed, R. R. (1997). Putative odour receptors localize in cilia of olfactory receptor cells in rat and mouse: a freeze-substitution ultrastructural study [corrected and republished in J Neurocytol 1997 Oct;26(10):691-706]. Journal of Neurocytology, 26, (5), 297-312.

Menco, B. P., Dodd, G. H., Davey, M. and Bannister, L. H. (1976). Presence of membrane particles in freeze-etched bovine olfactory cilia. Nature, 263, (5578), 597-9.

Menco, B. P. and Farbman, A. I. (1985). Genesis of cilia and microvilli of rat nasal epithelia during pre-natal development. I. Olfactory epithelium, qualitative studies. Journal of Cell Science, 78, 283-310.

Menco, B. P., Tekula, F. D., Farbman, A. I. and Danho, W. (1994). Developmental expression of G-proteins and adenylyl cyclase in peripheral olfactory systems. Light microscopic and freeze-substitution electron microscopic immunocytochemistry. Journal of Neurocytology, 23, (11), 708-27.

Meyer, M. R., Angele, A., Kremmer, E., Kaupp, U. B. and Muller, F. (2000). A cGMP-signaling pathway in a subset of olfactory sensory neurons. Proceedings of the National Academy of Sciences of the United States of America, 97, (19), 10595-600.

Michel, D., Moyse, E., Brun, G. and Jourdan, F. (1994). Induction of apoptosis in mouse [correction of rat] olfactory neuroepithelium by synaptic target ablation. Neuroreport, 5, (11), 1329-32.

Michel, W. C. and Ache, B. W. (1992). Cyclic nucleotides mediate an odor-evoked potassium conductance in lobster olfactory receptor cells. Journal of Neuroscience, 12, (10), 3979-84.

Min, Y. G., Rhee, C. S., Choo, M. J., Song, H. K. and Hong, S. C. (1994). Histopathologic changes in the olfactory epithelium in mice after exposure to sulfur dioxide. Acta Oto-Laryngologica, 114, (4), 447-52.

Miyamoto, T., Restrepo, D., Cragoe, E. J., Jr. and Teeter, J. H. (1992). IP3- and cAMP-induced responses in isolated olfactory receptor neurons from the channel catfish. Journal of Membrane Biology, 127, (3), 173-83.

Miyawaki, A., Matsushita, F., Ryo, Y. and Mikoshiba, K. (1994). Possible pheromone-carrier function of two lipocalin proteins in the vomeronasal organ. EMBO Journal, 13, (24), 5835-42.

Molday, R. S. (1996). Calmodulin regulation of cyclic-nucleotide-gated channels. Current Opinion in Neurobiology, 6, (4), 445-52.

Mombaerts, P., Wang, F., Dulac, C., Chao, S. K., Nemes, A., Mendelsohn, M., Edmondson, J. and Axel, R. (1996). Visualizing an olfactory sensory map. Cell, 87, (4), 675-86.

Mombaertsa, P. (1999). Seven-transmembrane proteins as odorant and chemosensory receptors. Science, 286, (5440), 707-11.

Mombaertsb, P. (1999). Molecular biology of odorant receptors in vertebrates. Annual Review of Neuroscience, 22, 487-509.

Monti Graziadei, P. P. and Graziadei, G. A. (1979). Neurogenesis and neuron regeneration in the olfactory system of mammals. I. Morphological aspects of differentiation and structural organization of the olfactory sensory neurons. Journal of Neurocytology, 8, (1), 1-18.

Moon, C., Jaberi, P., Otto-Bruc, A., Baehr, W., Palczewski, K. and Ronnett, G. V. (1998). Calcium-sensitive particulate guanylyl cyclase as a modulator of cAMP in olfactory receptor neurons. Journal of Neuroscience, 18, (9), 3195-205.

Moon C., Sung Y.K., Reddy R. and Ronnett, G.V. (1999). Odorants induce the phosphorylation of the cAMP response elements binding protein in olfactory receptor neurons. Proceedings of the National Academy of Sciences of the United States of America, 96, (25), 14605-610.

Morales, B., Labarca, P. and Bacigalupo, J. (1995). A ciliary K+ conductance sensitive to charibdotoxin underlies inhibitory responses in toad olfactory receptor neurons [published erratum appears in FEBS Lett 1995 Apr 10;362(3):347]. FEBS Letters, 359, (1), 41-4.

Morales, B., Madrid, R. and Bacigalupo, J. (1997). Calcium mediates the activation of the inhibitory current induced by odorants in toad olfactory receptor neurons. FEBS Letters, 402, (2-3), 259-64.

Mori, K., Mataga, N. and Imamura, K. (1992). Differential specificities of single mitral cells in rabbit olfactory bulb for a homologous series of fatty acid odor molecules. Journal of Neurophysiology, 67, (3), 786-9.

Mori, K., Nagao, H. and Yoshihara, Y. (1999). The olfactory bulb: coding and processing of odor molecule information. Science, 286, (5440), 711-5.

Morrison, E. E. and Costanzo, R. M. (1990). Morphology of the human olfactory epithelium. Journal of Comparative Neurology, 297, (1), 1-13.

Moulton, D. G. (1975) In Olfaction and Taste, Vol. V (Denton, D. A. and Coghlan, J. P., ed.), Academic Press, New York, pp. 111-114.

Moulton, D. G. and Beidler, L. M. (1967). Structure and function in the peripheral olfactory system. Physiological Reviews, 47, (1), 1-52.

Mozell, M. M. (1970). Evidence for a chromatographic model of olfaction. Journal of General Physiology, 56, (1), 46-63.

Muller, F., Bonigk, W., Sesti, F. and Frings, S. (1998). Phosphorylation of mammalian olfactory cyclic nucleotide-gated channels increases ligand sensitivity. Journal of Neuroscience, 18, (1), 164-73.

Mumm, J. S., Shou, J. and Calof, A. L. (1996). Colony-forming progenitors from mouse olfactory epithelium: evidence for feedback regulation of neuron production. Proceedings of the National Academy of Sciences of the United States of America, 93, (20), 11167-72.

N :

Nakamura, T. and Gold, G. H. (1987). A cyclic nucleotide-gated conductance in olfactory receptor cilia. Nature, 325, (6103), 442-4.

Nakamura, T., Tsuru, K. and Miyamoto, S. (1994). Regulation of Ca2+ concentration by second messengers in newt olfactory receptor cell. Neuroscience Letters, 171, (1-2), 197-200.

Nef, P., Heldman, J., Lazard, D., Margalit, T., Jaye, M., Hanukoglu, I. and Lancet, D. (1989). Olfactory-specific cytochrome P-450. cDNA cloning of a novel neuroepithelial enzyme possibly involved in chemoreception. Journal of Biological Chemistry, 264, (12), 6780-5.

Nef, P., Hermans-Borgmeyer, I., Artieres-Pin, H., Beasley, L., Dionne, V. E. and Heinemann, S. F. (1992). Spatial pattern of receptor expression in the olfactory epithelium. Proceedings of the National Academy of Sciences of the United States of America, 89, (19), 8948-52.

Nef, S. and Nef, P. (1997). Olfaction: transient expression of a putative odorant receptor in the avian notochord. Proceedings of the National Academy of Sciences of the United States of America, 94, (9), 4766-71.

Nekrasova, E., Sosinskaya, A., Natochin, M., Lancet, D. and Gat, U. (1996). Overexpression, solubilization and purification of rat and human olfactory receptors. European Journal of Biochemistry, 238, (1), 28-37.

Newman, M. P., Feron, F. and Mackay-Sim, A. (2000). Growth factor regulation of neurogenesis in adult olfactory epithelium. Neuroscience, 99, (2), 343-50.

Ngaia, J., Dowling, M. M., Buck, L., Axel, R. and Chess, A. (1993). The family of genes encoding odorant receptors in the channel catfish. Cell, 72, (5), 657-66.

Ngaib, J., Chess, A., Dowling, M. M., Necles, N., Macagno, E. R. and Axel, R. (1993). Coding of olfactory information: topography of odorant receptor expression in the catfish olfactory epithelium. Cell, 72, (5), 667-80.

Noe, J. and Breer, H. (1998). Functional and molecular characterization of individual olfactory neurons. Journal of Neurochemistry, 71, (6), 2286-93.

O :

Ohno, K., Kawasaki, Y., Kubo, T. and Tohyama, M. (1996). Differential expression of odorant-binding protein genes in rat nasal glands: implications for odorant-binding proteinII as a possible pheromone transporter. Neuroscience, 71, (2), 355-66.

Okano, M. and Takagi, S. F. (1974). Secretion and electrogenesis of the supporting cell in the olfactory epithelium. Journal of Physiology, 242, (2), 353-70.

Ottoson, D. (1956). Analysis of the electrical activity of the olfactory epithelium. Acta Physiol. Scand, 35 suppl. 22, 1-83.

P :

Pace, U., Hanski, E., Salomon, Y. and Lancet, D. (1985). Odorant-sensitive adenylate cyclase may mediate olfactory reception. Nature, 316, (6025), 255-8.

Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Le Trong, I., Teller, D. C., Okada, T., Stenkamp, R. E., Yamamoto, M. and Miyano, M. (2000). Crystal structure of rhodopsin: A G protein-coupled receptor [see comments]. Science, 289, (5480), 739-45.

Paolini, S., Scaloni, A., Amoresano, A., Marchese, S., Napolitano, E. and Pelosi, P. (1998). Amino acid sequence, post-translational modifications, binding and labelling of porcine odorant-binding protein. Chemical Senses, 23, (6), 689-98.

Paolini, S., Tanfani, F., Fini, C., Bertoli, E. and Paolo, P. (1999). Porcine odorant-binding protein: structural stability and ligand affinities measured by fourier-transform infrared spectroscopy and fluorescence spectroscopy. Biochimica et Biophysica Acta, 1431, (1), 179-88.

Parmentier, M., Libert, F., Schurmans, S., Schiffmann, S., Lefort, A., Eggerickx, D., Ledent, C., Mollereau, C., Gerard, C. and Perret, J. (1992). Expression of members of the putative olfactory receptor gene family in mammalian germ cells. Nature, 355, (6359), 453-5.

Parmentier, M., Vanderhaeghen, P., Schurmans , S., Libert, F. and Vassart, G. (1994). Génétique moléculaires des récepteurs olfactifs. Médecine/Science, 10, 1083-1090.

Paternostro, M. A. and Meisami, E. (1996). Essential role of thyroid hormones in maturation of olfactory receptor neurons: an immunocytochemical study of number and cytoarchitecture of OMP-positive cells in developing rats. International Journal of Developmental Neuroscience, 14, (7-8), 867-80.

Pelosi, P. (1994). Odorant-binding proteins. Critical Reviews in Biochemistry & Molecular Biology, 29, (3), 199-228.

Pelosi, P. (1996). Perireceptor events in olfaction. Journal of Neurobiology, 30, (1), 3-19.

Pelosi, P., Baldaccini, N. E. and Pisanelli, A. M. (1982). Identification of a specific olfactory receptor for 2-isobutyl-3-methoxypyrazine. Biochemical Journal, 201, (1), 245-8.

Pelosi, P. and Maida, R. (1995). Odorant-binding proteins in insects. Comparative Biochemistry & Physiology. Part B, Biochemistry & Molecular Biology, 111, (3), 503-14.

Pelosi, P. and Tirindelli, R. (1989) In Chemical Senses. Receptor Events and Transduction in Taste and Olfaction., Vol. 1 (Brand, J. G., Teeter, J. H., Cagan, R. H., Kare, M. R. and Dekker, M., ed.), New York and Basel, pp. 207-226.

Pes, D., Dal Monte, M., Ganni, M. and Pelosi, P. (1992). Isolation of two odorant-binding proteins from mouse nasal tissue. Comparative Biochemistry & Physiology - B: Comparative Biochemistry, 103, (4), 1011-7.

Pes, D., Mameli, M., Andreini, I., Krieger, J., Weber, M., Breer, H. and Pelosi, P. (1998). Cloning and expression of odorant-binding proteins Ia and Ib from mouse nasal tissue. Gene, 212, (1), 49-55.

Pes, D. and Pelosi, P. (1995). Odorant-binding proteins of the mouse. Comparative Biochemistry & Physiology. Part B, Biochemistry & Molecular Biology, 112, (3), 471-9.

Pevsner, J., Hou, V., Snowman, A. M. and Snyder, S. H. (1990). Odorant-binding protein. Characterization of ligand binding. Journal of Biological Chemistry, 265, (11), 6118-25.

Pevsner, J., Sklar, P. B. and Snyder, S. H. (1986). Odorant-binding protein: localization to nasal glands and secretions. Proceedings of the National Academy of Sciences of the United States of America, 83, (13), 4942-6.

Pevsner, J., Trifiletti, R. R., Strittmatter, S. M. and Snyder, S. H. (1985). Isolation and characterization of an olfactory receptor protein for odorant pyrazines. Proceedings of the National Academy of Sciences of the United States of America, 82, (9), 3050-4.

Pevsnera, J., Hwang, P. M., Sklar, P. B., Venable, J. C. and Snyder, S. H. (1988). Odorant-binding protein and its mRNA are localized to lateral nasal gland implying a carrier function. Proceedings of the National Academy of Sciences of the United States of America, 85, (7), 2383-7.

Pevsnerb, J., Reed, R. R., Feinstein, P. G. and Snyder, S. H. (1988). Molecular cloning of odorant-binding protein: member of a ligand carrier family. Science, 241, (4863), 336-9.

Pilpel, Y. and Lancet, D. (1999). The variable and conserved interfaces of modeled olfactory receptor proteins. Protein Science, 8, (5), 969-77.

Pixley, S. K. (1992). The olfactory nerve contains two populations of glia, identified both in vivo and in vitro. GLIA, 5, (4), 269-84.

Powell, T. P., Cowan, W. M. and Raisman, G. (1965). The central olfactory connexions. Journal of Anatomy, 99, (4), 791-813.

Q :

Qasba, P. and Reed, R. R. (1998). Tissue and zonal-specific expression of an olfactory receptor transgene. Journal of Neuroscience, 18, (1), 227-36.

R :

Rafols, J. A. and Getchell, T. V. (1983). Morphological relations between the receptor neurons, sustentacular cells and Schwann cells in the olfactory mucosa of the salamander. Anatomical Record, 206, (1), 87-101.

Raming, K., Krieger, J., Strotmann, J., Boekhoff, I., Kubick, S., Baumstark, C. and Breer, H. (1993). Cloning and expression of odorant receptors. Nature, 361, (6410), 353-6.

Rankin, M. L., Alvania, R. S., Gleason, E. L. and Bruch, R. C. (1999). Internalization of G protein-coupled receptors in single olfactory receptor neurons. Journal of Neurochemistry, 72, (2), 541-8.

Rawson, N. E., Eberwine, J., Dotson, R., Jackson, J., Ulrich, P. and Restrepo, D. (2000). Expression of mRNAs encoding for two different olfactory receptors in a subset of olfactory receptor neurons. Journal of Neurochemistry, 75, (1), 185-95.

Rawson, N. E., Gomez, G., Cowart, B., Brand, J. G., Lowry, L. D., Pribitkin, E. A. and Restrepo, D. (1997). Selectivity and response characteristics of human olfactory neurons. Journal of Neurophysiology, 77, (3), 1606-13.

Reed, R. R. (1998). Opening the window to odor space [comment]. Science, 279, (5348), 193.

Reed, R. R. (2000). Regulating olfactory receptor expression: controlling globally, acting locally [news; comment]. Nature Neuroscience, 3, (7), 638-9.

Reese, T. S. (1965). Olfactory cilia in the frog. Journal of Cell Biolology, 25, 209-230.

Ressler, K. J., Sullivan, S. L. and Buck, L. B. (1993). A zonal organization of odorant receptor gene expression in the olfactory epithelium. Cell, 73, (3), 597-609.

Ressler, K. J., Sullivan, S. L. and Buck, L. B. (1994). Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell, 79, (7), 1245-55.

Restrepo, D., Miyamoto, T., Bryant, B. P. and Teeter, J. H. (1990). Odor stimuli trigger influx of calcium into olfactory neurons of the channel catfish. Science, 249, (4973), 1166-8.

Restrepo, D. and Teeter, J. H. (1990). Olfactory neurons exhibit heterogeneity in depolarization-induced calcium changes. American Journal of Physiology, 258, (6 Pt 1), C1051-61.

Restrepo, D., Teeter, J. H. and Schild, D. (1996). Second messenger signaling in olfactory transduction. Journal of Neurobiology, 30, (1), 37-48.

Reuter, D., Zierold, K., Schroder, W. H. and Frings, S. (1998). A depolarizing chloride current contributes to chemoelectrical transduction in olfactory sensory neurons in situ. Journal of Neuroscience, 18, (17), 6623-30.

Rogers, K. E., Dasgupta, P., Gubler, U., Grillo, M., Khew-Goodall, Y. S. and Margolis, F. L. (1987). Molecular cloning and sequencing of a cDNA for olfactory marker protein. Proceedings of the National Academy of Sciences of the United States of America, 84, (6), 1704-8.

Ronnett, G. V., Cho, H., Hester, L. D., Wood, S. F. and Snyder, S. H. (1993). Odorants differentially enhance phosphoinositide turnover and adenylyl cyclase in olfactory receptor neuronal cultures. Journal of Neuroscience, 13, (4), 1751-8.

Ronnetta, G. V., Hester, L. D. and Snyder, S. H. (1991). Primary culture of neonatal rat olfactory neurons. Journal of Neuroscience, 11, (5), 1243-55.

Ronnettb, G. V., Parfitt, D. J., Hester, L. D. and Snyder, S. H. (1991). Odorant-sensitive adenylate cyclase: rapid, potent activation and desensitization in primary olfactory neuronal cultures. Proceedings of the National Academy of Sciences of the United States of America, 88, (6), 2366-9.

Roskams, A. J., Bethel, M. A., Hurt, K. J. and Ronnett, G. V. (1996). Sequential expression of Trks A, B, and C in the regenerating olfactory neuroepithelium. Journal of Neuroscience, 16, (4), 1294-307.

Roskams, A. J., Bredt, D. S., Dawson, T. M. and Ronnett, G. V. (1994). Nitric oxide mediates the formation of synaptic connections in developing and regenerating olfactory receptor neurons. Neuron, 13, (2), 289-99.

Roskams, A. J., Cai, X. and Ronnett, G. V. (1998). Expression of neuron-specific beta-III tubulin during olfactory neurogenesis in the embryonic and adult rat. Neuroscience, 83, (1), 191-200.

Rouquiera, S., Friedman, C., Delettre, C., van den Engh, G., Blancher, A., Crouau-Roy, B., Trask, B. J. and Giorgi, D. (1998). A gene recently inactivated in human defines a new olfactory receptor family in mammals. Human Molecular Genetics, 7, (9), 1337-45.

Rouquierb, S., Taviaux, S., Trask, B. J., Brand-Arpon, V., van den Engh, G., Demaille, J. and Giorgi, D. (1998). Distribution of olfactory receptor genes in the human genome [published erratum appears in Nat Genet 1998 May;19(1):102]. Nature Genetics, 18, (3), 243-50.

Rubin, B. D. and Katz, L. C. (1999). Optical imaging of odorant representations in the mammalian olfactory bulb. Neuron, 23, (3), 499-511.

S :

Samanen, D. W. and Forbes, W. B. (1984). Replication and differentiation of olfactory receptor neurons following axotomy in the adult hamster: a morphometric analysis of postnatal neurogenesis. Journal of Comparative Neurology, 225, (2), 201-11.

Sato, T., Hirono, J., Tonoike, M. and Takebayashi, M. (1994). Tuning specificities to aliphatic odorants in mouse olfactory receptor neurons and their local distribution. Journal of Neurophysiology, 72, (6), 2980-9.

Sautter, A., Zong, X., Hofmann, F. and Biel, M. (1998). An isoform of the rod photoreceptor cyclic nucleotide-gated channel beta subunit expressed in olfactory neurons. Proceedings of the National Academy of Sciences of the United States of America, 95, (8), 4696-701.

Savic, I., Gulyas, B., Larsson, M. and Roland, P. (2000). Olfactory functions are mediated by parallel and hierarchical processing. Neuron, 26, (3), 735-45.

Schandar, M., Laugwitz, K. L., Boekhoff, I., Kroner, C., Gudermann, T., Schultz, G. and Breer, H. (1998). Odorants selectively activate distinct G protein subtypes in olfactory cilia. Journal of Biological Chemistry, 273, (27), 16669-77.

Schild, D. and Lischka, F. W. (1994). Amiloride-insensitive cation conductance in Xenopus laevis olfactory neurons: a combined patch clamp and calcium imaging analysis. Biophysical Journal, 66, (2 Pt 1), 299-304.

Schild, D., Lischka, F. W. and Restrepo, D. (1995). InsP3 causes an increase in apical [Ca2+]i by activating two distinct current components in vertebrate olfactory receptor cells. Journal of Neurophysiology, 73, (2), 862-6.

Schild, D. and Restrepo, D. (1998). Transduction mechanisms in vertebrate olfactory receptor cells. Physiological Reviews, 78, (2), 429-66.

Schoenfeld, T. A., Clancy, A. N., Forbes, W. B. and Macrides, F. (1994). The spatial organization of the peripheral olfactory system of the hamster. Part I: Receptor neuron projections to the main olfactory bulb. Brain Research Bulletin, 34, (3), 183-210.

Schofield, P. R. (1988). Carrier-bound odorant delivery to olfactory receptors [news]. Trends in Neurosciences, 11, (11), 471-2.

Schwarting, G. A. and Crandall, J. E. (1991). Subsets of olfactory and vomeronasal sensory epithelial cells and axons revealed by monoclonal antibodies to carbohydrate antigens. Brain Research, 547, (2), 239-48.

Schwarting, G. A., Kostek, C., Ahmad, N., Dibble, C., Pays, L. and Puschel, A. W. (2000). Semaphorin 3A is required for guidance of olfactory axons in mice. Journal of Neurosciences, 15, (20), 7691-7697.

Schwartz Levey, M., Chikaraishi, D. M. and Kauer, J. S. (1991). Characterization of potential precursor populations in the mouse olfactory epithelium using immunocytochemistry and autoradiography. Journal of Neuroscience, 11, (11), 3556-64.

Schwob, J. E., Farber, N. B. and Gottlieb, D. I. (1986). Neurons of the olfactory epithelium in adult rats contain vimentin. Journal of Neuroscience, 6, (1), 208-17.

Schwob, J. E., Youngentob, S. L. and Mezza, R. C. (1995). Reconstitution of the rat olfactory epithelium after methyl bromide-induced lesion. Journal of Comparative Neurology, 359, (1), 15-37.

Segal, R. A., Takahashi, H. and McKay, R. D. (1992). Changes in neurotrophin responsiveness during the development of cerebellar granule neurons. Neuron, 9, (6), 1041-52.

Sengupta, P., Chou, J. H. and Bargmann, C. I. (1996). odr-10 encodes a seven transmembrane domain olfactory receptor required for responses to the odorant diacetyl. Cell, 84, (6), 899-909.

Serizawa, S., Ishii, T., Nakatani, H., Tsuboi, A., Nagawa, F., Asano, M., Sudo, K., Sakagami, J., Sakano, H., Ijiri, T., Matsuda, Y., Suzuki, M., Yamamori, T. and Iwakura, Y. (2000). Mutually exclusive expression of odorant receptor transgenes [see comments]. Nature Neuroscience, 3, (7), 687-93.

Shahana, K., Denaro, M., Gilmartin, M., Shi, Y. and Derman, E. (1987). Expression of six mouse major urinary protein genes in the mammary, parotid, sublingual, submaxillary, and lachrymal glands and in the liver. Molecular & Cellular Biology, 7, (5), 1947-54.

Shahanb, K., Gilmartin, M. and Derman, E. (1987). Nucleotide sequences of liver, lachrymal, and submaxillary gland mouse major urinary protein mRNAs: mosaic structure and construction of panels of gene-specific synthetic oligonucleotide probes. Molecular & Cellular Biology, 7, (5), 1938-46.

Sharon, D., Glusman, G., Pilpel, Y., Khen, M., Gruetzner, F., Haaf, T. and Lancet, D. (1999). Primate evolution of an olfactory receptor cluster: diversification by gene conversion and recent emergence of pseudogenes. Genomics, 61, (1), 24-36.

Shepherd, G. M. (1994). Discrimination of molecular signals by the olfactory receptor neuron. Neuron, 13, (4), 771-90.

Shinohara, H., Asano, T. and Kato, K. (1992). Differential localization of G-proteins Gi and Go in the accessory olfactory bulb of the rat. Journal of Neuroscience, 12, (4), 1275-9.

Shou, J., Rim, P. C. and Calof, A. L. (1999). BMPs inhibit neurogenesis by a mechanism involving degradation of a transcription factor [see comments]. Nature Neuroscience, 2, (4), 339-45.

Sicard, G. (1986). Electrophysiological recordings from olfactory receptor cells in adult mice. Brain Research, 397, (2), 405-8.

Sicard, G. and Holley, A. (1984). Receptor cell responses to odorants: similarities and differences among odorants. Brain Research, 292, (2), 283-96.

Singer, A. G., Macrides, F., Clancy, A. N. and Agosta, W. C. (1986). Purification and analysis of a proteinaceous aphrodisiac pheromone from hamster vaginal discharge. Journal of Biological Chemistry, 261, (28), 13323-6.

Singer, M. S., Hughes, T. E., Shepherd, G. M. and Greer, C. A. (1998). Identification of olfactory receptor mRNA sequences from the rat olfactory bulb glomerular layer. Neuroreport, 9, (16), 3745-8.

Singer, M. S., Shepherd, G. M. and Greer, C. A. (1995). Olfactory receptors guide axons [letter]. Nature, 377, (6544), 19-20.

Sklar, P. B., Anholt, R. R. and Snyder, S. H. (1986). The odorant-sensitive adenylate cyclase of olfactory receptor cells. Differential stimulation by distinct classes of odorants. Journal of Biological Chemistry, 261, (33), 15538-43.

Skoufos, E., Healy, M. D., Singer, M. S., Nadkarni, P. M., Miller, P. L. and Shepherd, G. M. (1999). Olfactory Receptor Database: a database of the largest eukaryotic gene family. Nucleic Acids Research, 27, (1), 343-5.

Snyder, D. A., Rivers, A. M., Yokoe, H., Menco, B. P. and Anholt, R. R. (1991). Olfactomedin: purification, characterization, and localization of a novel olfactory glycoprotein. Biochemistry, 30, (38), 9143-53.

Spinelli, S., Ramoni, R., Grolli, S., Bonicel, J., Cambillau, C. and Tegoni, M. (1998). The structure of the monomeric porcine odorant binding protein sheds light on the domain swapping mechanism. Biochemistry, 37, (22), 7913-8.

Steinlen, S., Klumpp, S. and Schultz, J. E. (1990). Guanylate cyclase in olfactory cilia from rat and pig. Biochimica et Biophysica Acta, 1054, (1), 69-72.

Strotmann, J., Wanner, I., Helfrich, T., Beck, A., Meinken, C., Kubick, S. and Breer, H. (1994). Olfactory neurones expressing distinct odorant receptor subtypes are spatially segregated in the nasal neuroepithelium. Cell & Tissue Research, 276, (3), 429-38.

Strotmann, J., Wanner, I., Krieger, J., Raming, K. and Breer, H. (1992). Expression of odorant receptors in spatially restricted subsets of chemosensory neurones. Neuroreport, 3, (12), 1053-6.

Sullivan, S. L., Adamson, M. C., Ressler, K. J., Kozak, C. A. and Buck, L. B. (1996). The chromosomal distribution of mouse odorant receptor genes. Proceedings of the National Academy of Sciences of the United States of America, 93, (2), 884-8.

Sullivan, S. L., Bohm, S., Ressler, K. J., Horowitz, L. F. and Buck, L. B. (1995). Target-independent pattern specification in the olfactory epithelium. Neuron, 15, (4), 779-89.

T :

Tegoni, M., Ramoni, R., Bignetti, E., Spinelli, S. and Cambillau, C. (1996). Domain swapping creates a third putative combining site in bovine odorant binding protein dimer [see comments]. Nature Structural Biology, 3, (10), 863-7.

Thomas, M. B., Haines, S. L. and Akeson, R. A. (1996). Chemoreceptors expressed in taste, olfactory and male reproductive tissues. Gene, 178, (1-2), 1-5.

Topazzini, A., Pelosi, P., Pasqualuetto, P. L. and Baldaccini, N. E. (1985). Specificity of a pyrazine binding protein from cow olfactory mucosa. Chemical Senses, 10, 45-49.

Touhara, K., Sengoku, S., Inaki, K., Tsuboi, A., Hirono, J., Sato, T., Sakano, H. and Haga, T. (1999). Functional identification and reconstitution of an odorant receptor in single olfactory neurons [published erratum appears in Proc Natl Acad Sci U S A 2000 Mar 28;97(7):3782]. Proceedings of the National Academy of Sciences of the United States of America, 96, (7), 4040-5.

Trask, B. J., Friedman, C., Martin-Gallardo, A., Rowen, L., Akinbami, C., Blankenship, J., Collins, C., Giorgi, D., Iadonato, S., Johnson, F., Kuo, W. L., Massa, H., Morrish, T., Naylor, S., Nguyen, O. T., Rouquier, S., Smith, T., Wong, D. J., Youngblom, J. and van den Engh, G. (1998). Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes. Human Molecular Genetics, 7, (1), 13-26.

Troemel, E. R., Chou, J. H., Dwyer, N. D., Colbert, H. A. and Bargmann, C. I. (1995). Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans. Cell, 83, (2), 207-18.

Troemel, E. R., Kimmel, B. E. and Bargmann, C. I. (1997). Reprogramming chemotaxis responses: sensory neurons define olfactory preferences in C. elegans. Cell, 91, (2), 161-9.

Trotier, D. and MacLeod, P. (1986). Intracellular recordings from salamander olfactory supporting cells. Brain Research, 374, (2), 205-11.

Tsuboi, A., Yoshihara, S., Yamazaki, N., Kasai, H., Asai-Tsuboi, H., Komatsu, M., Serizawa, S., Ishii, T., Matsuda, Y., Nagawa, F. and Sakano, H. (1999). Olfactory neurons expressing closely linked and homologous odorant receptor genes tend to project their axons to neighboring glomeruli on the olfactory bulb. Journal of Neuroscience, 19, (19), 8409-18.

U :

Utsumi, M., Ohno, K., Kawasaki, Y., Tamura, M., Kubo, T. and Tohyama, M. (1999). Expression of major urinary protein genes in the nasal glands associated with general olfaction. Journal of Neurobiology, 39, (2), 227-36.

V :

Vanderhaeghen, P., Schurmans , S., Parmentier, M. and Vasart, G. (1994). Les spermatozo´des ont-ils du nez ? Médecine/sciences, 11, (10), 1136-1139.

Vanderhaeghen, P., Schurmans, S., Vassart, G. and Parmentier, M. (1993). Olfactory receptors are displayed on dog mature sperm cells. Journal of Cell Biology, 123, (6 Pt 1), 1441-52.

Vanderhaeghen, P., Schurmans, S., Vassart, G. and Parmentier, M. (1997). Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. Genomics, 39, (3), 239-46.

Varnum, M. D. and Zagotta, W. N. (1997). Interdomain interactions underlying activation of cyclic nucleotide-gated channels. Science, 278, (5335), 110-3.

Vassar, R., Chao, S. K., Sitcheran, R., Nunez, J. M., Vosshall, L. B. and Axel, R. (1994). Topographic organization of sensory projections to the olfactory bulb. Cell, 79, (6), 981-91.

Vassar, R., Ngai, J. and Axel, R. (1993). Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium. Cell, 74, (2), 309-18.

Verhaagen, J., Oestreicher, A. B., Gispen, W. H. and Margolis, F. L. (1989). The expression of the growth associated protein B50/GAP43 in the olfactory system of neonatal and adult rats. Journal of Neuroscience, 9, (2), 683-91.

Verhaagen, J., Oestreicher, A. B., Grillo, M., Khew-Goodall, Y. S., Gispen, W. H. and Margolis, F. L. (1990). Neuroplasticity in the olfactory system: differential effects of central and peripheral lesions of the primary olfactory pathway on the expression of B-50/GAP43 and the olfactory marker protein. Journal of Neuroscience Research, 26, (1), 31-44.

Verma, A., Hirsch, D. J., Glatt, C. E., Ronnett, G. V. and Snyder, S. H. (1993). Carbon monoxide: a putative neural messenger [see comments] [published erratum appears in Science 1994 Jan 7;263(5143):15]. Science, 259, (5093), 381-4.

Viereck, C., Tucker, R. P. and Matus, A. (1989). The adult rat olfactory system expresses microtubule-associated proteins found in the developing brain. Journal of Neuroscience, 9, (10), 3547-57.

Vincent, F., Spinelli, S., Ramoni, R., Grolli, S., Pelosi, P., Cambillau, C. and Tegoni, M. (2000). Complexes of porcine odorant binding protein with odorant molecules belonging to different chemical classes. Journal of Molecular Biology, 300, (1), 127-39.

Vogl, A., Noe, J., Breer, H. and Boekhoff, I. (2000). Cross-talk between olfactory second messenger pathways. European Journal of Biochemistry, 267, (14), 4529-35.

Vosshall, L. B., Wong, A. M. and Axel, R. (2000). An olfactory sensory map in the fly brain. Cell, 102, (2), 147-59.

W :

Walensky, L. D., Roskams, A. J., Lefkowitz, R. J., Snyder, S. H. and Ronnett, G. V. (1995). Odorant receptors and desensitization proteins colocalize in mammalian sperm. Molecular Medicine, 1, (2), 130-41.

Wang, F., Nemes, A., Mendelsohn, M. and Axel, R. (1998). Odorant receptors govern the formation of a precise topographic map. Cell, 93, (1), 47-60.

Wang, M. M. and Reed, R. R. (1993). Molecular cloning of the olfactory neuronal transcription factor Olf-1 by genetic selection in yeast. Nature, 364, (6433), 121-6.

Wang, M. M., Tsai, R. Y., Schrader, K. A. and Reed, R. R. (1993). Genes encoding components of the olfactory signal transduction cascade contain a DNA binding site that may direct neuronal expression. Molecular & Cellular Biology, 13, (9), 5805-13.

Wellerdieck, C., Oles, M., Pott, L., Korsching, S., Gisselmann, G. and Hatt, H. (1997). Functional expression of odorant receptors of the zebrafish Danio rerio and of the nematode C. elegans in HEK293 cells. Chemical Senses, 22, (4), 467-76.

Weth, F., Nadler, W. and Korsching, S. (1996). Nested expression domains for odorant receptors in zebrafish olfactory epithelium. Proceedings of the National Academy of Sciences of the United States of America, 93, (23), 13321-6.

Wetzel, C. H., Oles, M., Wellerdieck, C., Kuczkowiak, M., Gisselmann, G. and Hatt, H. (1999). Specificity and sensitivity of a human olfactory receptor functionally expressed in human embryonic kidney 293 cells and Xenopus Laevis oocytes. Journal of Neuroscience, 19, (17), 7426-33.

Weyand, I., Godde, M., Frings, S., Weiner, J., Muller, F., Altenhofen, W., Hatt, H. and Kaupp, U. B. (1994). Cloning and functional expression of a cyclic-nucleotide-gated channel from mammalian sperm. Nature, 368, (6474), 859-63.

Williams-Hogarth, L. C., Puche, A. C., Torrey, C., Cai, X., Song, I., Kolodkin, A. L., Shipley, M. T. and Ronnett, G. V. (2000). Expression of semaphorins in developing and regenerating olfactory epithelium. Journal of Comparative Neurology, 423, (4), 565-78.

Wong, S. T., Trinh, K., Hacker, B., Chan, G. C., Lowe, G., Gaggar, A., Xia, Z., Gold, G. H. and Storm, D. R. (2000). Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice. Neuron, 27, (3), 487-497.

Wright, R. H. (1972). Stereochemical and vibrational theories of odour. Nature, 239, (5369), 226.

Wright, R. H. (1977). Odor and molecular vibration: neural coding of olfactory information. Journal of Theoretical Biology, 64, (3), 473-502.

Wright, R. H., Hughes, J. R. and Hendrix, D. E. (1967). Olfactory coding. Nature, 216, (113), 404-6.

Wright, R. H. and Robson, A. (1969). Basis of odour specificity: homologues of benzaldehyde and nitrobenzene. Nature, 222, (190), 290-2.

Y :

Yokoe, H. and Anholt, R. R. (1993). Molecular cloning of olfactomedin, an extracellular matrix protein specific to olfactory neuroepithelium. Proceedings of the National Academy of Sciences of the United States of America, 90, (10), 4655-9.

Yoshihara, Y., Kawasaki, M., Tamada, A., Fujita, H., Hayashi, H., Kagamiyama, H. and Mori, K. (1997). OCAM: A new member of the neural cell adhesion molecule family related to zone-to-zone projection of olfactory and vomeronasal axons. Journal of Neuroscience, 17, (15), 5830-42.

Yoshihara, Y. and Mori, K. (1997). Basic principles and molecular mechanisms of olfactory axon pathfinding. Cell & Tissue Research, 290, (2), 457-63.

Yu, S., Avery, L., Baude, E. and Garbers, D. L. (1997). Guanylyl cyclase expression in specific sensory neurons: a new family of chemosensory receptors. Proceedings of the National Academy of Sciences of the United States of America, 94, (7), 3384-7.

Z :

Zald, D. H. and Pardo, J. V. (1997). Emotion, olfaction, and the human amygdala: amygdala activation during aversive olfactory stimulation. Proceedings of the National Academy of Sciences of the United States of America, 94, (8), 4119-24.

Zhainazarov, A. B. and Ache, B. W. (1995). Odor-induced currents in Xenopus olfactory receptor cells measured with perforated-patch recording. Journal of Neurophysiology, 74, (1), 479-83.

Zhang, C., Finger, T. E. and Restrepo, D. (2000). Mature olfactory receptor neurons express connexin 43. Journal of Comparative Neurology, 426, (1), 1-12.

Zhao, H., Ivic, L., Otaki, J. M., Hashimoto, M., Mikoshiba, K. and Firestein, S. (1998). Functional expression of a mammalian odorant receptor [see comments]. Science, 279, (5348), 237-42.

Zheng, C., Feinstein, P., Bozza, T., Rodriguez, I. and Mombaerts, P. (2000). Peripheral olfactory projections are differentially affected in mice deficient in a cyclic nucleotide-gated channel subunit. Neuron, 26, (1), 81-91.

Zhuang, X., Belluscio, L. and Hen, R. (2000). GOLFalpha Mediates Dopamine D1 Receptor Signaling. J. Neurosci, 20, (16), RC91.

Zigman, J. M., Westermark, G. T., LaMendola, J., Boel, E. and Steiner, D. F. (1993). Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system. Endocrinology, 133, (6), 2508-14.

Zippel, H. P. (1993). Historical aspects of research on the vertebrate olfactory system. Naturwissenschaften, 80, (2), 65-76.

Zufall, F. and Leinders-Zufall, T. (1997). Identification of a long-lasting form of odor adaptation that depends on the carbon Monoxide/cGMP second-messenger system. Journal of Neuroscience, 17, (8), 2703-12.

Zupko, K., Poria, Y. and Lancet, D. (1991). Immunolocalization of cytochromes P-450olf1 and P-450olf2 in rat olfactory mucosa. European Journal of Biochemistry, 196, (1), 51-8.
haut de page 
page précédente sommaire page suivante

Cours de biologie  |  Articles de revue  |  Études  |  Offres d'emplois  |  Pense-bête  |  Sélection de livres  |  Nouveautés livres  |  Liens  |  Forum

© - Tous droits réservés.